Bioinformatics Research Scientist

3 days ago

Washington, United States Children's National Medical Center Full time

About the Role

The Children's National Medical Center is seeking a highly skilled Senior Bioinformatics Scientist to join our team at the Center for Cancer and Immunology Research (CCIR) and Brain Tumor Institute.

This position will play a critical role in advancing research focused on uncovering oncogenic mechanisms in pediatric brain tumors and identifying novel therapeutic targets through integrative genomics of host-tumor genome data.

As a Senior Bioinformatics Scientist, you will engage in translational research projects and contribute to tool development, such as interactive applications for visualizing complex genomic data.

You will work closely with researchers and clinicians within both Children's National as well as external partners to advance our understanding of pediatric oncology and genomics.

Main Responsibilities

  • Lead bioinformatics analyses on pediatric oncology datasets, including genomic, transcriptomic, and epigenomic data.
  • Design and implement downstream analytical workflows for high-throughput data using our GitHub, Docker, and AWS infrastructure, focusing on reproducibility, code efficiency, and scalability.
  • Collaborate on the Open Pediatric Cancer (OpenPedCan) Project.
  • Identify RNA neoepitope CAR-T or RNA vaccine targets, consisting of proteomic validation.
  • Utilize cloud-computing environments (e.g., AWS EC2) and/or high-performance computing (HPC) to support large-scale or memory-intensive analyses.
  • Participate in sprints and code reviews, ensuring high standards for reproducibility and documentation.
  • Engage with multidisciplinary teams, providing bioinformatics expertise to support collaborative research initiatives.

Requirements

  • Ph.D. in Bioinformatics, Computational Biology, or a related field, or equivalent industry experience.
  • At least five years of experience in bioinformatics, with expertise in Bash, R or Python, RShiny and or Python GUI applications such as streamlit, nicegui, dash, etc.
  • Proficiency with cloud-based or high-performance computing environments for bioinformatics workflows.
  • Strong experience with tools and best practices for reproducibility, including Git and Docker.
  • Proven experience with genomic data types such as single nucleotide variants (SNVs), copy number variants, fusions, RNA expression, methylation, proteomics, and splicing data.
  • Commitment to open science practices, including sharing and collaborating on code, data, and documentation.
  • Knowledge of pediatric oncology and genomics.

Preferred Skills

  • Strong organizational and project management skills, with the ability to work on multiple projects and teams.
  • Excellent communication skills, with the ability to work in cross-disciplinary teams.
  • Eligible to apply for young investigator grant funding.

Benefits and Work Environment

This full-time position offers a competitive salary range: $109,116.80 - $181,854.40. The ideal candidate will have a strong background in bioinformatics and be able to contribute to the advancement of pediatric oncology research.

  • Lead Bioinformatics Scientist for Pediatric Oncology Research

    7 days ago

    Washington, United States Children's National Medical Center Full time

    Job OverviewChildren's National Medical Center is seeking a highly skilled Senior Data Scientist to join our Rokita Lab at the Center for Cancer and Immunology Research (CCIR) and Brain Tumor Institute.About the RoleThis position involves leading bioinformatics analyses on pediatric oncology datasets, including genomic, transcriptomic, and epigenomic...

  • Cell Imaging and Bioinformatics

    4 weeks ago

    Washington, United States DataTecnica LLC Full time

    Are you interested in cellular imaging (particularly neuronal and glial cell types) and genomics to leverage open science in the fight against dementia? Then we have the job for you!DataTecnica (DT) invites applications for this currently open position at the new Center for Alzheimer’s and Related Dementias (CARD) at the National Institutes of Health. We...

  • Cell Imaging and Bioinformatics

    4 weeks ago

    washington, United States DataTecnica LLC Full time

    Are you interested in cellular imaging (particularly neuronal and glial cell types) and genomics to leverage open science in the fight against dementia? Then we have the job for you!DataTecnica (DT) invites applications for this currently open position at the new Center for Alzheimer’s and Related Dementias (CARD) at the National Institutes of Health. We...

  • Cell Imaging and Bioinformatics

    4 weeks ago

    Washington, United States DataTecnica LLC Full time

    Are you interested in cellular imaging (particularly neuronal and glial cell types) and genomics to leverage open science in the fight against dementia? Then we have the job for you!DataTecnica (DT) invites applications for this currently open position at the new Center for Alzheimer’s and Related Dementias (CARD) at the National Institutes of Health. We...

  • Cell Imaging and Bioinformatics

    3 weeks ago

    washington, United States DataTecnica LLC Full time

    Are you interested in cellular imaging (particularly neuronal and glial cell types) and genomics to leverage open science in the fight against dementia? Then we have the job for you!DataTecnica (DT) invites applications for this currently open position at the new Center for Alzheimer’s and Related Dementias (CARD) at the National Institutes of Health. We...

  • Computational Biology Research Scientist

    7 days ago

    Washington, Virginia, United States State of Virginia Full time

    About the PositionVirginia Tech's Cancer Research Center is seeking a highly motivated Postdoctoral Associate to join our team. As a Computational Biology Research Scientist, you will play a key role in advancing our understanding of malignant cell heterogeneity and tumor microenvironment remodeling.About the LabThe Mei Laboratory studies the complex...

  • Research Scientist

    7 days ago

    Washington, Washington, D.C., United States Virginia Tech University Full time

    Postdoctoral Position in Computational BiologyThe Mei Laboratory at the Fralin Biomedical Research Institute (FBRI) Cancer Research Center at Virginia Tech University is seeking a highly motivated Computational Biology postdoctoral researcher to join our team.Key Responsibilities:Conduct research in computational biology, focusing on the remodeling and...

  • Research Scientist

    2 days ago

    Washington, DC, United States The George Washington University Full time

    Special Instructions Employer will not sponsor for employment Visa status. Department Information Job Description Summary: The Biochemistry and Molecular Medicine department strives to deliver the highest quality of professional education and training, and conduct cutting edge research in the areas of biochemistry, molecular genetics, genomics, and...

  • Research Scientist

    6 days ago

    Washington, United States George Washington University Full time

    We are seeking a highly motivated Research Scientist to join our team at the George Washington University School of Medicine and Health Sciences. As a Research Scientist, you will be responsible for conducting research in various fields, including healthcare and health sciences.">The successful candidate will have a strong background in research and a PhD or...

  • Bioinformatics Specialist I

    2 days ago

    Washington, DC, United States The George Washington University Full time

    Job Description Summary Founded in 1824, the GW School of Medicine and Health Sciences (SMHS) is the 11th oldest medical school in the country and the first in the nation’s capital. Since its establishment, the school has been at the forefront of medical education, and has grown to include highly-ranked programs in the health and biomedical sciences. With...

  • Research Scientist

    7 days ago

    Washington, United States George Washington University Full time

    At George Washington University, we offer a unique opportunity to succeed in discovery with our state-of-the-art facilities and world-class faculty. Our researchers and faculty advance interdisciplinary and emerging solutions across campus.We are seeking a highly skilled Research Scientist to join our team. This role offers a competitive salary of $80,000 -...

  • Research Scientist

    6 days ago

    Washington, United States George Washington University Full time

    We are seeking a highly motivated and accomplished Research Scientist to join our team at George Washington University. This is an excellent opportunity to contribute to cutting-edge research in interdisciplinary fields.The successful candidate will have a strong background in scientific research, with expertise in experimental design, data analysis, and...

  • Research Scientist

    6 days ago

    Washington, United States George Washington University Full time

    We are seeking a highly motivated and accomplished Postdoctoral Associate to join our team at George Washington University. As a Research Scientist, you will have the opportunity to work in a dynamic environment with world-class faculty and researchers.">About the Opportunity">We offer a competitive salary of $ $60,000 per year, which reflects the level of...

  • Bioinformatics Specialist I

    2 days ago

    Washington, DC, United States The George Washington University Full time

    Please see Special Instructions for more details. Employer will not sponsor for employment Visa status I. DEPARTMENT INFORMATION Job Description Summary: Founded in 1824, the GW School of Medicine and Health Sciences ( SMHS ) is the 11th oldest medical school in the country and the first in the nation’s capital. Since its establishment, the school...

  • Research Scientist with Expertise in Microbiology and Public Health

    7 days ago

    Washington, Washington, D.C., United States Joint Research and Development, LLC Full time

    Job OverviewJoint Research and Development, LLC is seeking a highly qualified Intermediate Scientist to support health technology development initiatives for the Advanced Research Projects Agency for Health (ARPA-H).This role requires extensive experience in microbiological research and analysis.Key ResponsibilitiesProgram Analysis and Execution:Collaborate...

  • Research Scientist

    7 days ago

    Washington, United States MPOWIR Mentoring Physical Oceanography Women to Increase Retention Full time

    Company Overview\Friday Harbor Laboratories is a leading research institution focused on advancing our understanding of the ocean. Our team is committed to fostering a collaborative and inclusive environment that encourages innovation and excellence in marine research.","Salary">$60,000 - $80,000 per annum, depending on experience","">Job Description"We are...

  • Research Administrator, Biochemistry Department, GW University

    1 week ago

    Washington, United States The George Washington University Full time

    Imagine being part of a team that is at the forefront of medical education and research.The George Washington University's School of Medicine and Health Sciences (SMHS) is seeking a Research Administrator to join our dynamic department. This is an exciting opportunity for someone who wants to make a difference in the field of biochemistry and molecular...

  • Computer Scientist

    1 week ago

    Washington, United States Applied Research Associates Full time

    Description The Mission Concepts & Capabilitis (MCC) division of Applied Research Associates, Inc. (ARA) is seeking a motivated, energetic Computer Scientist to support the Navy in the development and application of cutting-edge high-performance computing (HPC) software and network architectures. This contingent position, expected to start late summer or...

  • Computer Scientist

    5 days ago

    Washington, United States Applied Research Associates Full time

    Description The Mission Concepts and Capabilities Division (MCC) of Applied Research Associates, Inc. (ARA) is seeking a motivated, energetic Computer Scientist to support the government in the development and application of high-assurance computer security systems hardware and software. This contingent position, expected to start late spring or early...

  • Principal Computer Scientist

    4 weeks ago

    Washington, United States Applied Research Associates Full time

    Description The Mission Concepts & Capabilitis (MCC) division of Applied Research Associates, Inc. (ARA) is seeking an energetic, responsive, Principal Computer Scientist to support the Navy in the development and application of cutting-edge high-performance computing (HPC) software and network architectures. This contingent position, expected to start late...