Chief Medicinal Chemistry Strategist

7 days ago


Étreux, Hauts-de-France, United States Tbwa ChiatDay Inc Full time

Nimbus Therapeutics is a nimble biotech company focused on immunology/inflammation, oncology, and metabolic diseases. We leverage our world-class discovery engine by combining computational chemists, structure-based drug design expertise (SBDD), and experienced medicinal chemists with diverse therapeutic area biologists and development teams.

As Chief Medicinal Chemistry Strategist, you will play a pivotal role in advancing multiple small molecule drug discovery campaigns and combine scientific decision-making with organizational leadership to drive projects from hit identification to development candidate.

This Role Involves:

  • Leading multidisciplinary drug discovery chemistry teams in a fast-paced, results-driven environment
  • Designing, implementing, and executing robust medicinal chemistry strategies to meet project objectives
  • Establishing and maintaining partnerships to leverage external expertise and resources
  • Collaborating effectively with various departments, functions, and leadership team members to align on project goals and strategies
  • Planning and allocating resources effectively to optimize project outcomes
  • Providing strategic, scientific, and managerial guidance within an outsourced medicinal and synthetic chemistry framework
  • Contributing to the overall scientific direction and success of the organization's current and future pipeline

To Be Successful in This Role, You Will Need:

  • A Ph.D. or equivalent in Synthetic Organic Chemistry, Medicinal Chemistry, or a related field
  • 10+ years of drug discovery experience within the biopharmaceutical industry, including a demonstrated strong track record of scientific innovation and success in delivering clinical candidates
  • An in-depth understanding of drug discovery processes, including ADME/PK, pharmacology, physicochemical property optimization, computational chemistry, and safety/toxicology considerations
  • An established record of success in applying structure-based drug design to clinical candidates
  • Experience leading multidisciplinary drug discovery teams with experience in hit identification to development candidate and beyond
  • Significant experience managing synthetic chemistry activities with CROs in Asia and/or Eastern Europe
  • Strong organizational, interpersonal, communication, and managerial skills with the ability to motivate and inspire teams to achieve scientific objectives

We Offer Competitive Compensation:

$183,000 - $250,000 per year based on experience

Nimbus is proud to be an equal opportunity employer and values diversity and inclusion.



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