Senior Principal Scientist, Process Chemistry Expert

4 weeks ago


Petersburg, Virginia, United States Phlow Corporation Full time
Job Overview

Phlow Corporation is seeking a highly skilled Senior Principal Scientist to join our Advanced Manufacturing R&D lab. As a key member of our team, you will be responsible for providing process chemistry support to ensure project deliverables are met on time and on budget.

Key Responsibilities
  • Design, synthesize, purify, and analyze chemical intermediates, target compounds, and impurities.
  • Maintain accurate records of all experiments and observations.
  • Author progress reports and present scientific results to team members.
  • Ensure a high level of safety awareness and conduct lab operations in a safe manner.
  • Contribute to the timely and accurate preparation of regulatory submissions.
  • Collaborate with Analytical Chemistry, EH&S, Engineering, Project Management, Quality Assurance, and Regulatory Affairs to ensure strong working relationships.
Requirements
  • Minimum of 5 years working in related roles in the pharmaceutical industry.
  • Broad range of functional expertise in modern synthetic organic chemistry, compound purification, and spectral analysis.
  • Experience with searching the chemical literature to evaluate potential solutions to synthetic problems.
  • Experience with common analytical techniques such as HPLC, GC, NMR, UV, and LC-MS.
Preferred Qualifications
  • Ph.D. with a minimum 5 years of experience, M.S. with a minimum 10 years of experience, or B.S. degree with a minimum 15 years of experience in Organic Chemistry, Pharmaceutical Sciences, or a related scientific field.
  • Process chemistry and API manufacturing experience on multi-kilogram scale.
  • Knowledge of ICH and cGMP requirements.
  • Experience working for a contract organization (CROs/CMOs/CDMOs).
Physical Requirements
  • Constantly required to see to utilize computer screens and monitors to perform job duties.
  • Frequently required to talk or hear to communicate with employees, candidates, vendors, and others.
  • Frequently required to reach with arms and hands performing repetitive motions and using finger dexterity.

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