Chief Science Innovator

7 days ago


San Diego, California, United States ScaleBio Full time

About Scale Biosciences, Inc.

ScaleBio is a pioneering life sciences technology and tools company dedicated to democratizing scalable, easy-to-adopt, extensible, cost-effective single-cell applications across various systems and sample types within the Life Sciences community. Our mission is built upon demonstrated technology with long-term investment commitments.

We are seeking an exceptional Chief Science Innovator with a passion for innovation, operations, and producing cutting-edge tools that benefit the life science community. The successful candidate will lead Continuous Process Improvement (CPI) initiatives to turn great ideas into reality by collaborating with cross-functional teams in operations, R&D, finance, field support, and quality. This role involves evaluating processes, products, and materials and implementing improvements to facilitate high-quality single cell RNA, methylation, and multi-omics product production and customer-centered product design and workflows.

The ideal candidate will be self-motivated, enthusiastic, have a proven track record of CPI, and bring knowledge of lean six sigma operational excellence to the organization. They will also contribute to maintaining scalable systems and process for product quality and traceability.

Key Responsibilities:

  • Leading the transfer of workflows, materials, protocols, quality testing from R&D to the manufacturing team.
  • Designing and executing experiments to address product stability, scalability, and alternative materials for kit production and services.
  • Collaborating with development teams to establish incoming material acceptance criteria, in-process QC, and final product quality specifications.
  • Serving as a technical expert or SME on projects and reporting data.
  • Supporting root cause analysis and production incidents with Scale's Quality Management System to deliver improvements.
  • Contributing to assay development to ensure best customer-facing workflows and processes are developed for customer success.
  • Supporting product quality and investigations for CAPAs, NCRs, and implementing corrective actions.
  • Leading and supporting product lifecycle management.
  • Effectively communicating with peers/management and reporting initiatives to corporate goals.
  • Cross-functionally working within and across the organization effectively as a team player.
  • Leading operational excellence initiatives in Manufacturing and R&D.

Your Qualifications:

  • An advanced degree in biology, chemistry, biochemistry, or a related field with 7+ years of biotechnology/pharmaceutical experience in Tech transfer or CPI.
  • A strong background in molecular biology techniques, including DNA/RNA purification and quantification, PCR/qPCR, Cell biology, enzymatic assays, and Next Generation Sequencing (NGS) techniques, RNA-based sequencing assays, methylation-based assays, single-cell or targeted enrichment assays.
  • Single-cell workflows and knowledge are a bonus.
  • A can-do attitude and creative problem-solving skills.
  • Management/supervisory experience and working with cross-functional teams.
  • Knowledge of traditional operational excellence processes: Lean Six Sigma, Kaizen, Gemba, visualizations, 5S, KanBan, standard work model, etc.
  • Ability to excel in a fast-paced, ambiguous, and changing landscape.
  • Strong attention to detail.
  • Proactive ability to anticipate problems and mitigate risk.

Compensation and Benefits:

We offer a competitive compensation package, including a base salary range of $155,000 - $175,000 USD, comprehensive health and dental benefits, a 401K retirement savings plan, state-of-the-art laboratory facilities, and an exciting and innovative culture with opportunities to enable novel single-cell technologies. To learn more about this opportunity, please visit our website at www.scale.bio.



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