Senior Bioanalytical Scientist
1 week ago
Arrowhead Pharmaceuticals is a clinical stage biopharmaceutical company that develops innovative medicines to treat intractable diseases. Our RNAi-based therapeutics leverage the natural pathway of gene silencing to address conditions with a genetic basis.
Salary and BenefitsWe offer a competitive salary range of $120,000—$140,000 USD, along with an excellent benefit package, including a comprehensive health insurance plan, 401(k) matching program, and opportunities for professional growth and development.
About the RoleWe are seeking a skilled Sr. Scientist, GLP Bioanalysis to join our Bioanalytical group within the Clinical Pharmacology Department. The successful candidate will focus on internal bioanalytical method development and qualification of biomarker assays, as well as oversee bioanalytical method transfer, validation, and sample analysis for early and late development phase programs.
Key Responsibilities:- Lead assigned projects, providing oversight of outsourced GxP bioanalytical validations and sample analysis from early to late development for pharmacokinetic and biomarkers studies.
- Track progress against project timelines, generate regular status updates, and communicate progress and issues to management and cross-functional teams.
- Perform scientific and data review, data analysis and interpretation, and troubleshoot complex method issues as needed.
- Develop and qualify bioanalytical assays via LC-MS/MS and immunoassays or other platforms for clinical biomarker studies.
- Explore new analytical platforms and lead lab organization and setup for biomarkers.
- Train other group members in biomarkers method development and qualification and biomarkers/PK project oversight.
To be considered for this role, you must have:
- A Ph.D. in Chemistry (or related field) with 5+ years of relevant GxP experience.
- Familiarity with GxP regulations and approaches to method validations, sample analysis, and data processing.
- Demonstrated method development experience with various analytical platforms and deep expertise with LC-MS/MS and immunoassays.
- Demonstrated project and time management skills.
- Experience with training other scientists and leading lab organization and processes.
- Excellent oral and written communication skills.
- The ability to thrive in a fast-paced, dynamic, multi-disciplinary, matrixed environment.
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