Senior Mechanical Engineer, Plastics NPI Expert

7 days ago


Pleasanton, California, United States 10X Genomics Full time

About 10x Genomics

At 10x Genomics, we're accelerating our understanding of biology to change the world. We empower scientists to advance their research and address questions they never thought possible.

Our teams are passionate about following their ideas and pursuing new discoveries in an inclusive environment. Behind every breakthrough is a talented team driving the life sciences industry forward.

We're seeking a Senior Mechanical Engineer, Plastics New Product Introduction (pNPI) to join our Manufacturing Systems Engineering (MSE) team. This key position will commercialize consumable products within Global Operations Engineering and involve close collaboration with Microfluidics, Supply Chain Management, and New Product Development teams.

Key Responsibilities
  • Transfer complex plastic components to volume manufacturing as a technical lead
  • Perform Design for Manufacturability analysis on new plastic components and provide feedback on designs with supplier and Manufacturing team input
  • Qualify new plastic components with suppliers to ensure vendor quality, yield, and reliability
  • Lead the transfer of new parts to suppliers utilizing compounding, molding, solvent bonding of thermoplastics and elastomers, COC, COP, and LSR
  • Organize and manage projects to improve costs and product yield, ensuring smooth production transfer of new designs to established volume manufacturers
  • Utilize Arena PLM and Oracle ERP systems to manage product lifecycle and manufacturing processes effectively
  • Conduct occasional supplier visits to support quality audits and new vendor capability assessments

The ideal candidate has a proven track record in supporting complex plastic components used in on-market equipment for the life science or medical device industry. They should possess a broad understanding of design and manufacturing of complex plastic systems and excel in solving complex problems.

We're looking for a professional with:

  • Bachelor's degree in Mechanical, Plastics, or Manufacturing Engineering
  • At least 8+ years of post-graduate industrial experience, preferably in biotechnology or life science engineering or manufacturing
  • Solid 3D mechanical design experience using CAD, with SolidWorks experience a plus
  • Proven ability to transfer conceptual designs into scalable, manufacturable plastic components
  • Experience with injection molding, co-molding, thermoforming, designing parts for plastic molding, iterating on mold parameters, and troubleshooting issues from molding
  • Experience with structured problem-solving methods and proficiency in using large data sets to drive decisions
  • Experience with Arena PLM and Oracle ERP systems, creating, managing, and reviewing engineering change orders, engineering drawings, purchase specifications, and receiving inspection reports
  • Strong understanding of geometric tolerancing per ASME Y14.5, dimensional stack-ups, inspection procedures, and metrology equipment
  • Ability to travel internationally as needed
  • Ability to perform under pressure and adapt to changes

Salary: $149,000-$201,000 USD. Base pay is just one component of our comprehensive total compensation package, which includes equity grants, health and retirement benefits, and annual bonus programs.



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