Director, Worldwide Medical Leader

4 weeks ago


Boston, Massachusetts, United States Takeda Pharmaceuticals Full time

As a Director, Worldwide Medical Leader at Takeda Pharmaceuticals, you will be responsible for leading the protein and antibody engineering team using state-of-the-art methodologies. You will have extensive scientific and managerial expertise to strategically guide the team toward Research objectives, operational efficiency, and scientific excellence, with a direct impact on multiple programs within the Research pipeline.

The primary goal for the team is the design and engineering core, the output of which is impactful contributions to biologics therapeutics (potency/affinity modulation, developability enhancement, bispecific design, library design), and to the creation and improvement of current discovery and engineering platforms.

You will work tightly with the in-house AI/ML team to lead the direction and integration of computational approaches such that these methods become the new paradigm for de-risking candidates to accelerate the identification of the best viable therapeutics.

As part of the Biotherapeutic Engineering team, you will report to the Head of the team and proactively engage with, and be deeply involved, including serving as biologics lead on programs across all our 3 disease areas (Oncology; Neurology; Gastroenterology).

**Key Responsibilities:**

  • Design of maturation libraries for display platforms (affinity/potency/stability) leveraging datasets, experience, and state-of-the-art software to improve lead candidates.
  • Contribute to continual deepening of the expertise through external network development, evaluating new opportunities in partnership with business development.
  • Ambassador for the biologics department, scientifically inputting to the project teams.
  • Organizational leader who has accountability for the performance and results of the core research function with managerial responsibility of a group of skilled members.
  • Develop the next generation of organizational and project leaders, acting as a champion of new opportunities. Excellent knowledge of data analysis tools to ensure thorough evaluation of datasets and information based next step decisions.
  • High level of diligence in all data tracking, uploading, and recording using data management systems within the department.
  • PhD degree in a scientific discipline with 10 years experience, or MS with 16 years experience, or BS with 18 years experience.
  • Outstanding expertise and depth of knowledge within a scientific area Keeps up with the up-to-date scientific advancement (e.g. competitive landscape, new technology, new research portfolio, and new partnership).


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