Antibody Discovery and Engineering Scientist

1 week ago


Watertown, Massachusetts, United States Scion Life Sciences Full time
About the Role

We are seeking a highly skilled and experienced Antibody Discovery and Engineering Scientist to join our team at Scion Life Sciences. As a key member of our research organization, you will be responsible for designing and executing antibody discovery campaign strategies using display technologies such as phage and/or yeast display.

Key Responsibilities
  • Antibody Discovery Campaign Strategies: Design and execute antibody discovery campaign strategies using display technologies such as phage and/or yeast display.
  • Protein Engineering: Design and execute protein/antibody engineering strategies such as error prone PCR, saturated mutagenesis, DNA shuffling, etc. to perform affinity maturation etc.
  • Molecular Biology Efforts: Responsible for molecular biology efforts, including cloning and sequence analysis.
  • Bi- Multi-Specific Antibody Design: Provide input into bi- multi-specific antibody design and evaluation.
  • Protein-Protein Interactions: Performing protein-protein interactions using appropriate methods (ie, SPR, BLI, ELISA) to achieve engineering and discovery program goals.
  • Therapeutic Candidate Selection: Provide critical input in therapeutic candidate selection based on an understanding of program goals.
  • Technology Evaluation: With support, evaluates new technologies aimed at expanding Antibody Discovery and Protein Engineering capabilities.
  • Instrumentation Expertise: Establishes expertise on critical instrumentation, coordinating support and service to maintain critical operations.
  • Data Analysis and Communication: Performs data analyses and maintain good record keeping (ELN). Synthesize data and communicate results with the team.
  • Team Management: Manage and nurture a small team.
Requirements
  • Education: PhD with 1-3yrs, MS with at least 5yrs or BS with at least 8 years of industry experience, in Biochemistry, Bioengineering, Antibody Engineering, or related field.
  • Experience: Experience with phage display and or yeast display is required.
  • Technical Skills: Experience with biochemistry techniques including protein quantitation, protein purification, and/or biophysical/biochemical assays.
  • Soft Skills: Excellent communication, interpersonal and organizational skills, excited to work in a highly collaborative environment.
Company Overview

Scion Innovations is a biotech incubator founded by Scion Life Sciences, a life science focused company formation VC firm. We are dedicated to creating proprietary therapeutics and intellectual property that will be spun out to create new companies. Our team is passionate about discovering and developing innovative biologics and other large molecules for various diseases and disorders of considerable unmet need.



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