Biological Research Scientist

6 days ago

San Diego, California, United States Scripps Research Full time
About Us

Scripps Research is a nonprofit biomedical institute recognized for its groundbreaking impact on innovation. With a rich legacy spanning over 100 years, we continue to push the boundaries of scientific discovery in immunology, infectious diseases, neuroscience, heart disease, and cancer.

Located in La Jolla, California, our institute comprises six research departments, multiple Nobel laureates, and a top-ranked graduate school. We collaborate with researchers from the Scripps Research Translational Institute and Calibr to merge foundational studies in biology, chemistry, and computer science with translational science.

Our Mission

We aim to cultivate new scientific leaders and expand the frontiers of knowledge to deliver medical breakthroughs that impact human health globally. If you have a passion for making a difference, this could be your opportunity to join our transformative team.

Celebrating a Century: Learn More

Job Title: Postdoctoral AssociateJob Summary

We are seeking a highly motivated Postdoctoral Associate who will lead their own project and perform mammalian cell culture, in vivo mouse experiments, in vivo genetic screens, quantitative TMT mass spectrometry proteomics, metabolomics, western blot, pulldowns, DNA cloning, immunostaining, confocal microscopy, high throughput screens, and bioinformatic data analysis.

Significant emphasis is placed on the professional development of the Postdoctoral Associate. More information on the project will be discussed during the interview process.

Lab Project Overview

To maintain homeostasis, organisms rely on internal signaling networks that orchestrate physiological responses across different tissues and organs. Intriguingly, perturbation in one tissue elicits secreted signals that transmit the information to other tissues and that these signals are important for maintenance of health and longevity.

S Secrets proteins are key components of interorgan signaling that coordinate organ functions by signaling over long distances. Destabilization of these interorgan signaling networks, responsible for the orchestration of physiological responses across organs, drives age-associated disease, including diabetes, cancer, or chronic inflammation.

Despite this, the composition and activity of interorgan communication networks and their impact on aging and disease remain poorly defined. The Droujinine Lab has developed novel methods to identify and characterize novel secreted factors that coordinate organ functions in homeostasis and disease in mammalian systems.

Specifically, we use proteomics and in vivo functional genomic screens to uncover the secreted proteins and cellular circuitry involved in homeostasis, obesity, and aging. To learn more, please visit www.scripps.edu/droujinine

Requirements
  • PhD degree in biology, physiology, neuroscience, chemical biology, biological engineering, or related discipline.
  • Experience in biologic techniques outlined in the position summary highly preferred but not required.
  • High motivation and independence in reading scientific literature and performing experiments.
Physical Requirements

This position works in a laboratory or vivarium environment. Further details of the physical requirements of established essential functions for this position will be addressed/discussed during the interview process.

Compensation

The estimated annual salary range for this position is $68,000 - $73,230, based on experience and qualifications. Comprehensive benefits include eligibility for retirement plans with employer contribution, full suite of Health and Welfare plans, access to Flexible Spending Accounts, competitive vacation and sick leave policies, free on-site Counseling Center, free on-site parking, and pet insurance.

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