Director, Pharmacology and In Vitro Research

4 weeks ago


Lincoln, Nebraska, United States Allergan Full time
About the Role

We are seeking an accomplished scientist and leader to join our Aesthetics Pharma Innovation Group at AbbVie. As a Director/Senior Principal Research Scientist, you will lead a team performing in vitro and ex vivo pharmacological research in the area of hair and skin biology.

Key Responsibilities
  • Design and deploy in vitro cellular and ex vivo assays to analyze pharmacological results for screening of novel molecules and discovery and validation of new targets.
  • Develop and execute a strategy in alignment with functional goals and key scientific objectives in early-stage discovery and during transition to development stage.
  • Partner with chemistry to design and create new molecular entities with desired pharmacological characteristics.
  • Liaise with toxicology, immunology, bioanalytical, clinical development, and commercial colleagues.
  • Manage project activities and professional development of a team of scientists through effective mentoring, guidance, and supervision.
  • Advance scientific expertise within the function and collaborate with cross-disciplinary teams to advance programs from research to development.
  • Develop forward-looking strategies to identify and implement novel assays, measurements, and technologies that increase throughput, quality, and reproducibility of pharmacological results.
  • Ensure the quality and effectiveness of key project results through sound design, early risk assessments, and implementation of fallback strategies.
Requirements
  • Extensive experience with pharmacological assays, focusing on in vitro (biochemical and cellular) pharmacology in an industrial research environment, with at least 10+ years of experience managing teams and cross-functional projects.
  • Understanding of small molecules and ability to partner with SMEs to design and create new molecular entities with desired pharmacological characteristics.
  • Direct experience with iPSC-derived cell models and CRISPR screens.
  • Proven track record of driving early to late-stage discovery programs.
  • Extensive knowledge and experience in dermatology (hair biology a plus).
  • At a minimum, conversant in -omics bioinformatics, pharmacokinetics, toxicologic and histologic assays and methods.
What We Offer

We offer a comprehensive package of benefits, including paid time off, medical/dental/vision insurance, and 401(k) to eligible employees. This job is eligible to participate in our short-term and long-term incentive programs.



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