Physician Research Health Scientist

3 weeks ago

Tarrytown, New York, United States BioSpace, Inc. Full time

We are seeking a dedicated physician-scientist with a strong background in human genetics to join our multi-disciplinary Cardiovascular, Metabolic and Skeletal disease Therapeutic Area Genetics (TAG) team at BioSpace, Inc.

This role will involve taking a leading part in the TAGs translational genetics program, which includes multimodal phenotyping in our vast collection of cohorts, designing and implementing large-scale genetic and epidemiologic investigations, mining data to identify potential targets for treatment and prevention of a wide array of human diseases, and driving translation of genetic insights.

You will work in close collaboration with various colleagues at BioSpace, Inc. and its affiliates, including scientists and clinicians in our pre-clinical biology and clinical development teams.

This position will grant you the opportunity to develop deep expertise in the applications of human genetics to all stages of drug discovery and development, and to play a leading role in the discovery and translation of tomorrow's transformative therapies.

Key Responsibilities:

  • Designing and implementing large-scale human genetics studies
  • Mining and interpreting genetic association results to identify causal genes and variants, and to prioritize candidate drug targets
  • Leading or contributing to the writing of scientific reports and publications
  • Working with colleagues in clinical development to apply genetic data and insights to the design, conduct or interpretation of clinical research activities
  • Using your clinical experience and medical knowledge to define high-quality and refined phenotypes for genetic discovery and target validation
  • Collaborating with industry and academic partners in collaborations of strategic interest to the TAG

Requirements:

  • A strong background in and knowledge of human genetics or genetic epidemiology
  • Training and experience in translational human genetics, genetic epidemiology (or related fields), and strong quantitative skills
  • Familiarity with the applications of statistical genetics to gain medical insights, including polygenic scores, quantitative traits analyses, rare variant analyses, GWAS, and Mendelian randomization
  • Familiarity with command-line interface, programming languages, and statistical software (e.g. R, Python)
  • Experience with the use of genetics in combination with other omics technologies

What We Offer:

  • A comprehensive benefits package, including health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels
  • An inclusive and diverse culture that values collaboration, innovation, and excellence

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations.

The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.

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