Research Scientist
4 weeks ago
Takeda is a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. We are seeking a highly skilled Research Scientist to join our team as a Cell Engager Therapies In Vivo Pharmacologist. In this role, you will be responsible for the discovery and development of novel therapeutics in the T cell engager space, supporting new and ongoing pipeline programs.
Key Responsibilities- Develop and maintain in vivo models to test the biological efficacy of therapeutic agents for oncology indications.
- Design and execute in vivo efficacy models in xenograft and PDX models.
- Participate in the analysis of in vivo studies to help establish PK/PD/efficacy relationships.
- Execute experiments with minimal supervision and deliver comprehensive high-quality data sets to enable decision-making.
- Collaborate with cross-functional teams to advance development candidates to IND.
- Interpret results of complex experiments and prepare comprehensive technical or project reports.
- Maintain laboratory notebooks and follow laboratory practices in compliance.
- MS with 4+ years' experience or BS with 6+ years' of research experience in a lab setting working with animals.
- Experience in industry required, in animal facilities.
- Proficiency with in vivo efficacy rodent models, including mouse syngeneic, xenograft, and PDX models.
- Experimental skills, including mammalian tissue culture, in vivo model development, drug administration by multiple routes, and blood/tissue collection.
- Hands-on basic experience with multi-color flow cytometry, ELISA, MSD, and other standard cell-based and non-cell-based biochemical assays.
- Use of scientific databases and applications for data management and data analysis.
Takeda is a patient-focused company that inspires and empowers employees to grow through life-changing work. We are certified as a Global Top Employer and offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.
BenefitsWe understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees and strive to be more transparent with our pay practices. U.S. based employees may be eligible for short-term and/or long-term incentives, medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others.
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