Upstream Process Development Leader
1 week ago
Job Overview
EPM Scientific is seeking a highly skilled Upstream Process Development Leader to join our team. As a key member of our development team, you will be responsible for leading the design, optimization, and scale-up of upstream processes for biologics production.
The ideal candidate will have extensive experience in cell culture, fermentation, bioreactor operations, and process scale-up. A strong scientific background in cell line development, media optimization, and bioreactor operation is essential. Proven track record in process characterization, validation, and regulatory submissions is also required.
Key Responsibilities:
- Foster a collaborative environment that promotes innovation, scientific excellence, and continuous improvement.
- Establish clear objectives, KPIs, and development plans for team members.
- Oversee the development and optimization of upstream processes, including cell culture, media development, bioreactor design, and process control strategies.
- Collaborate with cross-functional teams to ensure seamless integration of upstream processes into the overall development pipeline.
- Lead efforts in scaling up upstream processes from bench-scale to pilot- and manufacturing-scale, ensuring process consistency and robustness.
Requirements:
- Master's or Ph.D. in Chemical Engineering, Biochemistry, Biotechnology, or a related field with 8 - 10 years of experience in upstream process development; with at least 5 years in a leadership role within the biopharmaceutical industry.
- Expertise in cell culture, fermentation, bioreactor operations (single-use and stainless steel), and process scale-up.
- Strong scientific background in cell line development, media optimization, and bioreactor operation.
- Familiarity with automated process development tools and high-throughput screening technologies.
Estimated Salary: $150,000 - $180,000 per year, depending on experience. This is a full-time position based in Boston, MA. We offer a competitive benefits package, including health insurance, retirement plan, and paid time off. If you are a motivated and experienced professional looking for a new challenge, please apply now.
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