Scientific Director, DMPK and Pharmacokinetics Specialist

3 days ago


Étreux, Hauts-de-France, United States Takeda Pharmaceutical Full time
Role Overview

We are seeking a highly skilled Scientific Director, DMPK and Pharmacokinetics Specialist to join our team at Takeda Pharmaceutical in Cambridge, Massachusetts.

Job Summary

The successful candidate will be responsible for leading cross-functional teams in the development of DMPK strategies, providing scientific expertise on ADME and PK-related issues, and driving innovative approaches in support of drug discovery and development.

Main Responsibilities
  • Lead Cross-Functional Teams: Collaborate with project teams to develop and implement DMPK strategies, ensuring alignment with program objectives and regulatory requirements.
  • Provide Scientific Expertise: Leverage deep knowledge of DMPK principles, ADME, and PK/PD modeling to address complex scientific challenges and drive innovation in drug discovery and development.
  • Drive Innovation: Develop and communicate clear DMPK strategies, champion novel scientific approaches, and stay up-to-date with industry trends and advancements.
Key Requirements
  • PhD in a Relevant Discipline: A PhD degree in a scientific discipline, such as pharmacology, toxicology, or chemistry, with a strong background in DMPK principles.
  • Experience in DMPK: At least 3+ years of experience in DMPK, with a proven track record of accomplishments in managing DMPK core activities and taking compounds into preclinical and/or clinical development.
  • Leadership and Communication Skills: Excellent leadership and communication skills, with the ability to interact and collaborate with colleagues from diverse scientific disciplines.
  • Technical Skills: Proficiency in software tools such as Phoenix, Watson, GastroPlus, and Simcyp, as well as experience with PBPK modeling and IND module compilation.
What We Offer
  • Competitive Salary: $163,500 - $259,750 per annum, commensurate with experience.
  • Benefits Package: Comprehensive benefits package, including medical, dental, vision insurance, 401(k) plan, company match, short-term and long-term disability coverage, basic life insurance, tuition reimbursement, paid volunteer time off, company holidays, and well-being benefits.
  • Opportunities for Growth: Opportunities for professional growth and development, including training programs, mentorship, and career advancement opportunities.
About Takeda

Takeda is a values-led company committed to creating a diverse workforce and providing equal employment opportunities to all employees and applicants without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information, or other protected characteristic.



  • Étreux, Hauts-de-France, United States Takeda Pharmaceuticals Full time

    About the RoleTakeda Pharmaceuticals is a forward-thinking, world-class R&D organization dedicated to unlocking innovation and delivering life-changing therapies to patients worldwide. By focusing our R&D efforts on key therapeutic areas, we drive transformative growth and push the boundaries of what is possible.As a Scientific Director, Global DMPK&M, you...


  • Étreux, Hauts-de-France, United States Merck Full time

    Job DescriptionIn this exciting role, you will lead drug metabolism and pharmacokinetic (DMPK) efforts as a project-team representative, regularly interacting with multi-disciplinary discovery teams and partners from other functions within our research division.The ideal candidate will have experience supporting immunology or oncology-based programs, with a...


  • Étreux, Hauts-de-France, United States Takeda Pharmaceuticals Full time

    At Takeda Pharmaceuticals, we are a pioneering force in the biopharmaceutical industry, committed to unlocking innovation and delivering transformative therapies to patients worldwide.About the RoleWe seek an exceptional individual to fill the position of Chief Research Director, Scientific Leadership, in our Cambridge, Massachusetts office. This role will...


  • Étreux, Hauts-de-France, United States Page Mechanical Group Inc Full time

    Medexus Pharma, a leading specialty pharmaceutical company, seeks an experienced Scientific Medical Specialist to join our team. With a strong North American commercial platform and a growing portfolio of innovative and rare disease treatment solutions, we're committed to advancing patient care through cutting-edge science and expertise.About the RoleThe...


  • Étreux, Hauts-de-France, United States EPM Scientific - Phaidon International Full time

    Job OverviewEPM Scientific - Phaidon International is seeking a highly skilled Medical Science Liaison to join our team.CompensationThe estimated salary for this role is $120,000 - $180,000 per year, depending on experience and qualifications.About the RoleThis Medical Science Liaison position will focus on rare diseases and field-based scientific exchange....


  • Étreux, Hauts-de-France, United States EPM Scientific Full time

    Job SummaryWe are seeking an exceptional Lead Technical Director of Biopharma Services to join our team at EPM Scientific. As a highly technical, director-level professional, you will play a key role in building and maintaining strategic partnerships with biopharma and CRO companies.This is an ideal opportunity for professionals with extensive experience...


  • Étreux, Hauts-de-France, United States Takeda Pharmaceuticals Full time

    Job SummaryWe are seeking a highly experienced Scientific Director to lead our Bioanalytical and Biomarker Science and Technologies department in the Oncology Therapeutic Area.About the RoleThis strategic role will serve as a single point of contact for the Oncology PTM, QCP, DDU, TAU, and other cross-functional partners. The successful candidate will work...


  • Étreux, Hauts-de-France, United States Mass General Brigham Full time

    Company OverviewMass General Brigham is a renowned healthcare system dedicated to providing exceptional patient care and advancing medical research.Job SummaryWe are seeking a highly motivated Scientific Research Support Specialist to join our team in the laboratory of Dr. Stelios Smirnakis at the Brigham and Women's Hospital.Estimated Salary: $65,000 -...


  • Étreux, Hauts-de-France, United States Solid Biosciences Full time

    Job Title: Clinical Assays Director - BioanalyticsThe solid foundation of Solid Biosciences is built on advancing a portfolio of neuromuscular and cardiac programs, including SGT-003, a differentiated gene therapy candidate for the treatment of Duchenne, AVB-401, a gene therapy program for the treatment of BAG3 mediated dilated cardiomyopathy, AVB-202-TT, a...


  • Étreux, Hauts-de-France, United States nomic Full time

    About UsNomic is a cutting-edge biotechnology company dedicated to revolutionizing the field of proteomics. Founded with the mission of making biology easier to measure, we have developed innovative solutions to tackle some of the most complex challenges in protein profiling.Our team combines DNA nanotechnology, high-dimensional flow cytometry, laboratory...


  • Étreux, Hauts-de-France, United States EPM Scientific - Phaidon International Full time

    We are seeking a highly experienced Senior Biopharma Technical Director to lead our team in genetic testing and development. Based in Boston, San Diego, or the San Francisco Bay Area, you will be responsible for overseeing the successful implementation, maintenance, and growth of pharmaceutical and biotech partnerships.This role requires a strategic thinker...


  • Étreux, Hauts-de-France, United States Thermo Fisher Scientific Full time

    About the RoleWe are seeking a highly skilled Quality Assurance Data Review Specialist to join our team at Thermo Fisher Scientific. In this role, you will play a critical part in ensuring the quality and accuracy of our data, driving business growth, and contributing to our mission of enabling our customers to make the world healthier, cleaner, and...


  • Étreux, Hauts-de-France, United States Takeda Pharmaceutical Full time

    OverviewTakeda Pharmaceutical is a global company transforming patient care through innovative specialty pharmaceuticals and exceptional patient support programs.We are seeking a highly skilled Scientific Leader to join our team as Director Translational Biomarker Lead Inflammation/Autoimmune Disease in Early Clinical Development (ECD). This role will focus...


  • Étreux, Hauts-de-France, United States Thermo Fisher Scientific Full time

    Job Overview">Thermo Fisher Scientific Inc. is a leading provider of analytical instruments and life sciences solutions. We are seeking an experienced Sr Manager, Sales to join our team.">About the Role">This leadership position will be responsible for managing a team of sales representatives in the Life Sciences sector. The ideal candidate will have a...


  • Étreux, Hauts-de-France, United States EPM Scientific Full time

    About EPM ScientificWe are a biotechnology company focused on developing innovative therapies for rare and underserved diseases. Our mission is to leverage cutting-edge science to target key biological pathways for genetic conditions.Job SummaryThe Director of Regulatory Operations will lead and manage the regulatory strategy and operations for global...


  • Étreux, Hauts-de-France, United States Tbwa ChiatDay Inc Full time

    OverviewWe are seeking a highly skilled Medical Science Liaison to join our team at Praxis Precision Medicines. As a key member of our scientific engagement team, you will be responsible for building strong relationships with healthcare professionals, academic institutions, and patient advocacy groups.The ideal candidate will have experience in the field of...


  • Étreux, Hauts-de-France, United States Servier Pharmaceuticals Full time

    Job DescriptionServier Pharmaceuticals is seeking a highly skilled Medical Oncology Training Specialist to join our team.The ideal candidate will have 5+ years of experience in the pharmaceutical industry, with at least 2 years as a Medical Science Liaison (MSL) in oncology. They will be responsible for contributing to the development and execution of the...


  • Étreux, Hauts-de-France, United States Vertex Pharmaceuticals Full time

    Vertex PharmaceuticalsWe are seeking a Senior Artificial Intelligence Director to lead our machine learning efforts in the Data and Computational Sciences team. This role will drive strategic partnerships with other data science groups across the network, develop and implement novel methods for predictive models and generative models, and apply them to small...


  • Étreux, Hauts-de-France, United States Takeda Pharmaceutical Full time

    About the Role:Takeda Pharmaceuticals is seeking a highly experienced Director, Antibody Engineering Leader to join its Global Biologics Department. As a key member of the team, you will be responsible for leading the protein and antibody engineering team using state-of-the-art methodologies. Your extensive scientific and managerial expertise will guide the...


  • Étreux, Hauts-de-France, United States Takeda Pharmaceuticals Full time

    About the RoleTakeda Pharmaceuticals is a global biopharmaceutical leader that is committed to delivering innovative therapies to patients worldwide.We are seeking a highly experienced Senior Biologics Program Director to join our team in Boston, MA. This is an exceptional opportunity to lead biologics programs from early discovery through IND and be...