Senior Computational Researcher

5 days ago

South San Francisco, California, United States Software Guidance and Assistance, Inc. Full time

Company Overview

Software Guidance and Assistance, Inc. (SGA) is a women-owned business providing technology and resource solutions to solve complex IT problems with a personal approach.

We value customer service, employee development, and quality in everything we do. Our mission is to stand out by delivering innovative solutions and exceptional results.

Salary

The estimated annual salary for this position is between $120,000 and $180,000 based on industry standards and location in South San Francisco, CA.

Job Description

We are seeking a talented Computational Scientist to join our Cancer Immunogenomics team in gRED Computational Sciences. The successful candidate will have a strong analytical background in computational biology and immuno-oncology, particularly focusing on T cell biology.

Responsibilities:

  • Collaborate with scientists in Oncology to analyze large-scale single-cell and bulk RNA, TCR, ADT, and ATAC-seq datasets to address scientific hypotheses and deliver novel insights.
  • Develop analytical approaches to integrate and interpret these data, delivering insights into disease biology and mechanisms of action to propel our pipeline and clinical research goals.
  • Coordinate the processing and standardization of newly incoming datasets to make them analysis-ready.
  • Document code, analysis processes, and findings, including standardization of analytical workflows.
  • Presentation of findings to the Cancer Immunogenomics group and Oncology collaborators.

Required Skills and Qualifications:

To succeed in this role, you will need:

  • Extensive experience in large-scale single-cell data analysis (RNA, TCR, ADT, ATAC), including gold-standard methods and novel, advanced analytical techniques such as multimodal data integration methods, cell phenotyping approaches, clonotype analysis, and TCR-sequence analysis.
  • Expertise in (immuno)-oncology, innate immunity, and/or T cell biology.
  • A PhD (or Master's with significant experience) in Computational Biology, Bioinformatics, or a related field.
  • Proficiency in R, Python, and shell scripting.
  • Experience working with Git and high-performance computing.
  • High self-motivation and commitment to delivering high-quality results.
  • Ability to produce high-quality analysis results with minimal supervision, including meeting key deadlines and making sensible independent decisions.
  • Excellent communication skills and experience working as part of a team.
  • Curiosity and desire to learn more about computational biology and immuno-oncology biology.

Benefits:

At SGA, we offer a diverse team built on core values of customer service, employee development, and quality. We strive to provide a supportive work environment where our consultants can grow professionally and personally. You'll enjoy benefits like competitive compensation, opportunities for professional growth, and a chance to work on challenging projects that drive innovation.

Others:

Please visit our company website at https://sgainc.com/ to learn more about our services and culture. We are an Equal Opportunity Employer committed to diversity, equity, and inclusion. If you require assistance with accommodations, please reach out to us.

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