VP, Clinical Development Leader

4 weeks ago


Boston, Massachusetts, United States Vigil Neuroscience, Inc. Full time
Job Title: VP, Clinical Development Leader

Vigil Neuroscience, Inc. is seeking a highly experienced VP, Clinical Development Leader to oversee the clinical sciences of all Vigil's clinical stage programs with particular focus on rare disease and Alzheimer's disease.

The ideal candidate will have a proven track record leading new medicines through all stages of CNS clinical development to marketing authorization and approval. They will be responsible for providing clinical/medical leadership and support for Vigil's Alzheimer's disease and rare CNS indications programs as well as working closely with the CMO to further develop the early pipeline.

The VP will lead the design and contribute to the execution of the clinical development programs and provide direct oversight and management of clinical and medical aspects of clinical trials. They will also be responsible for protocol development, interpretation of results, and authoring of key clinical documents.

The successful candidate will have outstanding leadership skills with the ability to influence, able to make decisions and stand by them. They will be highly visible at all levels of the organization and must be able to build trust and credibility walking in the door.

Key Responsibilities:

  • Provide robust, innovative Clinical and Medical leadership for Vigil Neurosciences Clinical Development function (phases 1 through 3b).
  • Lead the design and contribute to the execution of the clinical development programs and provide direct oversight and management of clinical and medical aspects of clinical trials.
  • Provide medical monitoring support of ongoing and future clinical trials and act as the company's safety physician.
  • Responsible for protocol development, interpretation of results, and authoring of key clinical documents.
  • Lead interactions and maintain strong, close, and collaborative relationships with Key Opinion Leaders, Investigators, and other clinical stakeholders in support of clinical development programs in lockstep with corporate strategy.
  • Interface effectively with other departments, including Clinical Development Operations, Biometrics, Clinical Pharmacology in design and conduct of the clinical programs.
  • Lead/participate in project teams and relevant cross-functional sub-teams to ensure tactical alignment and execution; and works with external contract research organizations (CROs).
  • Adhere to regulatory requirements of study conduct and industry standards of Good Clinical Practice as well as VIGIL's SOPs.
  • Present scientific information at scientific conferences as well as clinical study investigator meetings.
  • Create and maintain a positive and productive work environment and exhibit exceptional leadership capabilities by creating trust and respect with other colleagues in Vigil.
  • Support critical evaluations and recommendations of business development opportunities.


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