Research Director In Vitro Antibody Discovery

1 week ago


Étreux, Hauts-de-France, United States Takeda Pharmaceuticals Full time
Associate Director Research In Vitro Antibody Discovery

About the role:

In this challenging and rewarding role, you will lead a team of scientists in the discovery and optimization of therapeutic antibodies, utilizing cutting-edge in vitro platforms and technologies. As a key member of our Biotherapeutic Engineering team, you will be responsible for advancing programs from discovery to IND, collaborating with internal and external groups to drive efficiency and transparency, and contributing to the development of novel antibody-based therapeutics.

Responsibilities:

- Scientific Leadership:

- Set high standards for the effectiveness of execution and rigor of thought, leveraging expertise in antibody-based discovery and optimization using yeast and phage in vitro platforms.

- Provide innovative guidance on strategies for candidate profiles, optimization approaches, and efficient workflow progression.

- Mine and triage antibody repertoires to progress viable therapeutic molecules, incorporating NGS-based sequence analysis and driven by functional readouts.

- Foster a highly innovative and focused mindset, identifying and driving efficient paths for workflow progression.

- Set excellent strategy within the sub-team and empower innovation.

- Contribute to the continual deepening of expertise through external network development.

- People Leadership:

- Organize and lead a small team, empowering and mentoring them in their mission to generate therapeutic biologics.

- Utilize an enterprise mindset with a broad view across the portfolio, informing resource allocation and prioritization of programs under direct remit.

- Develop the next generation of scientists and leaders, acting as a champion of new opportunities.

- Lead the team through in-lab presence, designing and executing discovery/optimization campaigns, including affinity maturation, developability, and technology development.

- Program Involvement:

- Serve as an ambassador for the biologics department, scientifically inputting to project teams and helping set standards for excellent and focused triage of molecules.

- Collaborate with internal/external groups for high efficiency and transparency, enabling swift progression of molecules.

- Other:

- Possess excellent knowledge of data analysis tools, ensuring thorough evaluation of datasets and information-based next-step decisions.

- Demonstrate high diligence in all data tracking, uploading, and recording using data management systems.

- Key involvement and due diligence for external interactions, collaborations, and workflows.

- Contribute to the preparation of patents, documentation for IND, and publications.

Requirements:

- PhD degree in a scientific discipline with 7+ years of experience, or MS with 13+ years of experience, or BS with 15+ years of experience, and 5 years of industry experience required.

- 5 years of managerial experience required.

- Keeps up-to-date with scientific advancements, including the competitive landscape, new technologies, research portfolios, and partnerships.

About Takeda:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best-in-class patient support programs.

Takeda is a patient-focused company that inspires and empowers you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do.

We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Join our team of motivated and dedicated professionals who are passionate about making a difference in patients' lives.

We offer a competitive compensation package, including a base salary range of $149,100.00 - $234,300.00, and a comprehensive benefits program, including medical, dental, vision insurance, a 401(k) plan, and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits.

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