Senior Analytical Research Scientist
6 days ago
Bachem is a leading innovation-driven company specializing in the development and manufacture of peptides and oligonucleotides. With over 50 years of experience and expertise, Bachem provides products for research, clinical development, and commercial application to pharmaceutical and biotechnology companies worldwide and offers a comprehensive range of services. Bachem operates internationally with headquarters in Switzerland and locations in Europe, the US, and Asia. The company is listed on the SIX Swiss Exchange.
Job OverviewThe Principal Scientist, Analytical Research and Development plays a critical role in Quality Control (QC) to support production operations for all production manufacturing, process development, and service order activities. This position works closely with process development, production manufacturing, QC material testing, QC IPC, and QC API testing to understand and align analytical strategies. As a key member of cross-departmental collaboration, this individual fosters clear communication and accountability. They proactively provide solutions to resolve analytical challenges to support internal and external customers in a timely manner.
Key Responsibilities- Independently plan, execute, and summarize analytical activities to support process R&D, production, CMC, and QC.
- Maintain cross-functional channels of communication to stay focused on implementing analytical strategy.
- Work closely with QC teams studying product attributes to align internal/external customer needs with planned analytical activities.
- Provide guidance and help peers and junior scientists for troubleshooting abnormal results.
- Independently conduct and document investigations related to analytical activities.
- Monitor and evaluate the impact of new industry guidance and trends of advanced analytical technology on analytical operations.
- Be a technical liaison between the QC teams and other cross-functional teams.
- Participate in the planning of QC strategy to support projects, other production, and R&D activities.
- Continuously improve working efficiency through streamlining of the analytical process and introduction of new technology.
- Build or expand analytical capabilities as needed.
- Develop and maintain an in-depth understanding of scientific principles associated with analytical activities.
This role requires:
- A B.S. in chemistry or a related scientific field with 12 years' industry experience, or an M.S. in chemistry or a related scientific field with 10 years' industry experience, or a Ph.D. in chemistry or a related scientific field with 7 years' industry experience.
- Experience working in GMP manufacturing and laboratory testing.
- Knowledge of current Good Manufacturing Practices (cGMP), Good Laboratory Practices (GLP), and Good Documentation Practices (GDP).
- Experience with HPLC (SEC, IC)/UPLC, GC, KF, Amino Acid Analysis, MS, MS/MS sequencing, and LC-MS.
- Strong hands-on instrumentation experience using HPLC, GC, UV-VIS, LC-MS, spectrophotometer, FT-IR spectroscopy, Karl Fischer, wet chemistry, etc.
- Experience in writing standard operating procedures (SOPs), test methods, technical protocols, and reports.
- Experience in method development, validation, and method transfer.
Bachem offers a competitive salary, annual performance bonus, a generous benefits package including comprehensive Medical/Dental/Vision coverage, 401(k) plan with employer contribution, and paid vacation, personal, and sick days.
CORPORATE SOCIAL RESPONSIBILITYBachem takes responsibility for future generations by careful handling of resources and avoiding environmental risks. We continually improve our ecological performance and develop and implement new approaches for enhancing employees' environmental awareness. EcoVadis has awarded Bachem Platinum Medal status in their assessment of Bachem.
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