Protein Scientist

7 days ago

Watertown, Massachusetts, United States Dragonfly Therapeutics, Inc. Full time

At Dragonfly Therapeutics, Inc., we are committed to discovering, developing, and commercializing novel therapies that harness the body's immune system. As a Protein Scientist - Biophysics and Biochemistry Specialist, you will play a critical role in our team by providing biophysical and biochemical characterization of our candidates.

The estimated salary for this position is $120,000 - $180,000 per year, based on industry standards and location. Your responsibilities will include:

Key Responsibilities:
  • Biophysical and Biochemical Characterization: Perform comprehensive protein analytics using techniques such as size-exclusion chromatography (SEC-MALS), hydrophobic interaction chromatography (HIC), differential scanning calorimetry (DSC)/differential scanning fluorimetry (DSF), capillary electrophoresis (CE-SDS), and capillary isoelectric focusing (cIEF).
  • Developability Assessments: Plan, coordinate, and conduct in-depth developability assessments to inform lead candidate selection by evaluating stability, aggregation propensity, and structural integrity.
  • Implementation of new technologies: Stay up-to-date on new and emerging technologies, evaluating assays/instrumentation, internalizing and developing methods that add to the characterization toolbox.

To be successful in this role, you will need:

Requirements:
  • A B.Sc. in Biochemistry, Biochemical Engineering, Chemistry, or related discipline, with 8+ years of relevant industrial experience, or an M.Sc. in Biochemistry, Biochemical Engineering, Chemistry, or related discipline, with 6+ years.
  • Strong hands-on experience with protein analytics techniques such as SEC, HIC, DSC/DSF, CE-SDS, and cIEF.
  • Proficiency in characterizing post-translational modifications, protein aggregation, and assessing protein stability.
  • Excellent data analysis and interpretation skills, with familiarity using statistical tools and software for data processing.

We offer a dynamic work environment, competitive salary, and opportunities for professional growth and development.

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