Senior Research Chemist Position in HIV-1 Integrase Inhibitors Development

1 week ago


Frederick, Maryland, United States National Cancer Institute Full time
About the Opportunity

We are seeking a highly motivated and skilled synthetic organic chemist or medicinal chemist to join our research team at the National Cancer Institute (NCI) Center for Cancer Research (CCR). As a Senior Research Chemist, you will be part of an interdisciplinary team focused on developing innovative solutions for HIV-1 integrase strand transfer inhibitors (INSTIs).

The successful candidate will have expertise in designing and synthesizing complex organic molecules, particularly heterocyclic compounds. You will collaborate with our team to design, execute, and analyze experiments to develop next-generation INSTIs that retain antiviral efficacy against resistant mutant forms of integrase.

This is a full-time Training Position (Starting stipend: $65,100, bonuses may apply) with excellent opportunities for professional growth and development. Our state-of-the-art facilities and collaborative environment make CCR an ideal place to advance your career.

Key Responsibilities
  • Design, synthesize, and characterize complex organic molecules, including heterocyclic compounds
  • Collaborate with the research team to develop and implement experimental strategies for INSTI development
  • Analyze data and contribute to the publication of research findings
Requirements and Qualifications

To be considered for this position, you must have:

  • A Doctoral degree in synthetic or medicinal chemistry with expertise in multi-step synthesis and spectral analysis
  • Experience synthesizing chiral heterocyclic compounds
About Frederick

Frederick is a vibrant city located just outside of Washington, D.C., offering a unique blend of small-town charm and big-city amenities. With its excellent schools, balanced economy, and highly educated workforce, Frederick is an ideal place to live and work.



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