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Director, Statistics
3 months ago
ROLE SUMMARY
The primary responsibility and effort for the position is statistics-specific collaboration focusing on health economics and patient-reported outcomes and other clinical outcome assessments in oncology, inflammation & immunology, and other therapeutic areas. Responsibility extends to methodological research to improve the design, conduct, analysis, and interpretation of studies. In addition, given that the Statistical Research & Data Science Center, in which the position is housed, develops scientific collaborations to advance patient-centered development methodologies, the position may invite external publications and presentations (along with other professional activities).
- Collaborate in the development and post-approval environment through consultation and implementation of statistical techniques related to HEOR based on state-of-the-art research.
- Enhance statistical expertise in value-based drug development among Pfizer HEOR scientists, statisticians, and clinicians through active engagement and leadership in research methodology and content-specific areas.
ROLE RESPONSIBILITIES
- Provide expert statistical support to HEOR leads in the design, analysis, reporting, and interpretation of clinical outcome assessments (patient-reported, clinician-rated observer-rated, and performance-based outcomes) and health economics in HEOR projects involving clinical trials and observational studies, including those in development supporting drug approval and reimbursement, HTA, as well as other post-approval activities, in order to inform decision-making and also to guide medical strategy and the scientific narrative through publications and external presentations.
- Partner with HEOR scientists, other HEOR statisticians, clinical statisticians, clinicians, statistical programmers, and others to develop and implement an effective plan to leverage HEOR data.
- Participate in HEOR regular meetings as needed and engage in proactive communications with project leads to better understand scientific and business needs.
- Provide computational and statistical advice on complex analytic issues supporting Pfizer’s HEOR projects.
- Develop, implement, and promote methodologies based on state-of-the-science computing and statistical research and dissemination of the results both internally and externally.
- Provide a strong presence for Pfizer with HTA, regulatory and professional organizations to influence knowledge generation and content of regulatory guidelines to support the adaption of health economics and patient-reported and other clinical outcome assessments.
- Develop effective collaborations with relevant non-statistical researchers.
- Be up-to-date on training and compliance with all Pfizer SOPs as required based on the assigned curriculum.
BASIC QUALIFICATIONS
- Ph.D. in biostatistics or related discipline with 7+ years of experience with patient-reported outcomes, health economics, health technology assessment, and outcomes research methodology used in clinical trials and observational studies.
- Displayed leadership experiences and capabilities including: the ability to influence and collaborate with diverse group of peers in a complex cross-functional environment, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
PREFERRED QUALIFICATIONS
- Experience with advanced knowledge of psychometrics, econometrics, and biometrics such as validation of health measurement scales, longitudinal data analysis, missing data methods, multiple comparisons techniques, cost-effectiveness analysis, generalized linear models, meta-analysis, real-world data analysis, and conjoint analysis.
- Experience with different phases of drug development, from Phase 2 to Phase 4, and the associated regulatory and reimbursement involved.
- Evidence of creative thought-leadership, professional presence, and scholarship through publications and presentations.
- Effective verbal and written communication skills in relating to colleagues and associates both inside and outside the organization.
Work location: Site based/Hybrid
LI-PFE
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting e
