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Research Associate I, Ex-vivo

4 months ago

Rockville, United States Champions Oncology Inc. Full time

**TITLE AND CLASSIFICATION**: Research Associate I, Ex Vivo

**REPORTING LOCATION**: Rockville, MD

The primary objective of the Research Associate I, Ex Vivo is to perform cross-functional laboratory assays with a focus on in vitro/In vivo studies. Assist in the development and execution of novel assays including collecting and processing data. Duties and responsibilities include:

- Contribute to the development of SOPs and assay workflows for pre-clinical and clinical assays.
- Contribute to data processing and preparation for client presentation.
- Perform basic and advanced cell culture to characterize growth and survival under treatment by client test agents through the use of 2-D and 3-D cell-based assays.
- Contribute to the development and execution of 3-D co-culture assays including primary, PDX, and immune cells.
- Efficiently plan and execute cell line scheduling for in vivo studies.
- Perform molecular biology endpoints including qRT-PCR, ELISA, Western Blot, and Luminex.
- Responsible for operating and assisting in development of high throughput automated laboratory systems including liquid handlers, dosing units, plate readers, and high content imaging equipment.
- Maintenance of laboratory and supply inventory.
- Contribute to the culture and demeanor of the ex vivo group by encouraging group cohesion and teamwork.
- Other duties may be assigned verbally at any time.

**KNOWLEDGE, SKILLS, AND ABILITIES**:

- Expertise in cell culture and cell-based assays.
- Experience handling primary cells, tumor tissue, and various blood products including serum/plasma, whole blood, and PBMCs.
- Proficiency with one or more additional molecular biology techniques including qRT-PCR, ELISA, Western Blot, and Luminex.
- Experience with flow cytometry is preferred but not required.
- Demonstrated ability to work effectively and productively in a team-oriented environment while maintaining a strong sense of integrity and confidentiality.
- Creative problem-solving skills and the ability to exercise sound and accurate judgment in making timely decisions.
- Strong planning, organizational, computer, written and verbal communication skills.
- Demonstrated accountability, initiative, and responsibility for own work.
- Ability to observe safety and security procedures.
- Ability to assist with other tasks/duties as needed in a small company environment.

**EDUCATION AND EXPERIENCE**:

- BS or MS degree with 0-2 years of relevant experience required. Preferred field of study in biology, or related sciences.
- This is an entry-level position, where experience working in or adjacent to an animal facility is preferred.

**PHYSICAL DEMANDS AND WORK ENVIRONMENT**:

- Must be able to sit and use hands to finger, handle and feel.
- Must be able to lift and move packages weighing up to 50 pounds.
- Must be able to sit for long periods of time using a computer in a typical office environment in a multi-level facility
- Some activities require repetitive motion and reaching, pulling or pushing.
- In carrying out the duties of the job there will be frequent exposure to fumes and chemical hazards.
- Duties performed routinely require exposure to blood, body fluid and tissue.
- This description reflects management’s assignment of essential functions, it does not proscribe or restrict the tasks that may be assigned. We celebrate diversity and are committed to creating an inclusive environment for all employees._