Postdoctoral Associate

1 week ago

Durham, United States Duke University Full time

School of Medicine

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

This position will support several of our ongoing projects related to our studies examining the role of the tumor-intrinsic NLRP3 inflammasome pathway in immunotherapy resistance. This will require experience in tissue culture work, flow cytometry, animal handling and experimentation, qrt-PCR, Western blot, as well as the execution and analysis of RNAseq/scRNAseq. The individual in this position will be expected to keep accurate lab notes, perform experimental troubleshooting, discuss ongoing work and research trajectory both in group lab meetings and in one-on-one meetings with the PI, while also keeping abreast of the literature in the areas related to each project. This individual will work under a senior research scientist and will be working in collaboration with another post-doctoral associate, a post-bac research assistant, and two laboratory technicians.

Minimum Qualifications

Education

PhD Degree with a background in tumor immunology

Experience

* Interest and experience in working with murine tumor models required


* Significant experience in multi-parameter flow cytometry and in the design of cell-based assays required



Skills

* Excellent verbal and written communication skills in English with good organizational and analytical abilities


* Capable of working independently on assigned projects while thriving in a team-oriented environment



Preferences

* Experience in performing and analyzing bulk RNAseq/scRNAseq preferred


* Interest and experience in conducting spatial transcriptomic studies preferred


* Experience in conducting proximity ligation assays and fluorescence in situ hybridization on tumor tissue specimens preferred


* Previous grant writing experience preferred



Job Code: 00003820 POSTDOCTORAL ASSOCIATE

Job Level: 00

Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

Nearest Major Market: Durham

Nearest Secondary Market: Raleigh

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