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Research Associate, Senior

4 months ago

Durham, United States Duke University Full time

Position Description:

The Graves laboratory within the Department of Pediatrics is a translational research lab focused on the biology of drug resistance and progression in osteosarcoma. We are seeking an experienced research analyst to take a leadership role within the lab on projects utilizing pre-clinical models (including patient-derived organoids, pulmonary metastasis assays, and in vivo mouse xenografts) in the study of chemotherapy-resistant osteosarcoma

The Research Associate, Sr. will work under the direct supervision of Dr. Laurie Graves and will be expected to carry out research related to actively and prospectively funded projects, including collaborating with other laboratory researchers, clinical research team members, bioinformaticians, and biostatisticians. The candidate will need to independently develop experiments, analyze and interpret data, and document all research activities and data for subsequent use in publications and grant applications.

This position will be supported for two years with the potential for extension based on funding.

The ideal candidate will have:

* Experience working with mammalian cell culture, patient-derived models (organoids, cell lines) and mouse models of cancer (xenografts)
* Experience performing western blotting, RNA/DNA extractions, qRT-PCR, and genomics-based analysis of cancer cell lines, including gene expression profiling and next-generation sequencing
* Familiarity with bioinformatic and biostatistical approaches for the analysis of sequencing and proteomic data
* Desire to conduct team-based science in close collaboration with clinicians, statisticians, and regulators
* Excellent verbal and written English communication skills with outstanding organizational and analytical abilities

Interested candidates should send CVs to Dr. Laurie Graves (laurie.graves@duke.edu) for consideration. Select candidates will undergo a virtual interview and finalists will be

interviewed in-person at Duke University.

Min Degree Requirements:

Ph.D. or equivalent doctorate (e.g. Sc.D., M.D., D.V.M.).

Other Credential/Experiential Requirements:

The appointee must have greater than 5 years of postdoctoral training.

Minimum Qualifications

Education

See job description for education requirements.

Experience

See job description for requirements.

Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

Nearest Major Market: Durham

Nearest Secondary Market: Raleigh