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Research Associate I

4 months ago

Monrovia, United States City of Hope Full time

Join the transformative team at City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes,

and other life-threatening illnesses. City of Hope's growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix. our dedicated and compassionate employees are driven by a common mission: To deliver the cures of tomorrow to the people who need them today.

We seek a Research Associate candidate within the multidisciplinary research team headed by Dr. Ajay Goel, Professor and Chair Department of Molecular Diagnostics and Experimental Therapeutics and Associate Director of Basic Sciences, City of Hope Comprehensive Cancer. Our research is focused on translational research on the genomic and epigenomic characterization of various gastrointestinal cancers (GI), including colorectal, pancreatic, and gastric cancers.

Some of the key research topics in our laboratory include:

* Developing ctDNA and cfRNA-based liquid biopsy biomarkers for cancer diagnosis, prognosis, and predictive responses to various therapies.
* Study the epigenetic basis of GI cancers (e.g., aberrant DNA methylation, histone modifications, and non-coding RNAs).
* The genetic basis of early-onset and familial/hereditary colorectal cancers.
* The role of the tumor microenvironment, stem cells, immune regulation, and identification of novel targeted therapies.
* The role of extracellular vesicles/exosomes in cancer pathogenesis and their role as disease biomarkers.

As a successful candidate, you will:

* Maintain various aspects of lab management, including maintenance and upkeep of reagent and clinical specimen inventories, ordering, lab safety, and regulatory tasks.
* Ensure that all laboratory activities comply with each procedure(s) by utilizing safety procedures and guidelines in handling, storage, and disposal of bio-hazardous, infectious, and toxic material.
* Perform a variety of routine and non-routine laboratory research experiments nd record and validate results for accuracy and completeness.
* Perform Cancer Genetics and Epigenetics techniques and general lab maintenance that assists in conducting an Investigator's Research Project.
* Be responsible for accurately recording work performed, including results and methodology.

Your qualifications should include:

* Bachelor's or master's degree; master's degree preferred.
* Two years of laboratory experience with a bachelor's degree or 3 years of related research/ laboratory experience with a master's degree
* Assist and perform various molecular biology techniques, such as tissue culture, flow cytometry (analysis), and molecular tests, according to the Laboratory's Standard Operating Procedures.

City of Hope is an equal opportunity employer. To learn more about our commitment to diversity, equity and inclusion, please click here.