Principal Scientist, Analytical Development
2 weeks ago
Pacira BioSciences, Inc. is a leading provider of non-opioid pain management and regenerative health solutions dedicated to improving outcomes for health care practitioners and their patients. Our in-depth knowledge of non-opioid pain management, coupled with our passion for advancing patient care, drives our commitment to providing solutions that address unmet medical needs and improve clinical results.
Why work with us?
Rarely do you have an opportunity to do work that really matters. What drives us is our mission. What makes us successful are our people. At Pacira, you are part of an inclusive culture that fosters collaboration, growth, and innovative thinking - a place where you can make an impact and help change the standard of care in non-opioid pain management. Be part of our movement, let’s pursue excellence together.
Summary:
The purpose of this position is to provide gene therapy expertise, management of analytical development efforts, and general contribution to the gene therapy program.
Essential Duties & Responsibilities:
The following statements are intended to describe the general nature and level of work being performed by an individual assigned to this job. Other duties may be assigned.
- Manage the external development, qualification, and validation of analytical release and characterization methods for the helper dependent adenoviral gene therapy program.
- Manage multiple stability and/or comparability programs and critically evaluate the experimental results.
- Work closely with other departments for manufacturing efforts including internal and external collaborative organizations.
- Contribute to documents for regulatory submissions and/or review.
- Represent CMC at project team meetings as needed.
- Provide cross-training and guidance from within CMC to ensure a high functioning program.
- Maintain high level of technical knowledge in areas of responsibility.
- Apply the knowledge, skills and experience obtained to increase efficiency in solving new problems.
Supervisory Responsibilities:
This position may have supervisory responsibility.
Education and Experience:
The position requires a PhD in biology, chemistry, or a related field with at least 8 years of experience in development or a related role. Alternatively, candidates with an MS in a relevant field can be considered if they have a minimum of 12 years of experience in a similar role. Strong preference for experience within the CGT field.
Knowledge, Skills, and Abilities:
- Extensive knowledge of the analytical techniques and trends within adenoviral CGT, particularly molecular and cellular biology.
- Thorough understanding of the principals upon which CMC analytical and process development methodology is based.
- Extensive knowledge of GMP, regulatory requirements, guidelines and standard CGT practices.
- Ability to develop experimental plans for characterization and optimization of existing processes.
- Strong organizational skills (e.g. daily tasks, documentation, archived information).
- Strong interpersonal skills (e.g. working with other teams and organizations to achieve shared goals).
- Proficient in the use of computers and widely used workplace applications (e.g. Microsoft Office, Outlook, graphing software, etc.).
- Hands-on approach with a strategic and operational focus; capable decision maker in the execution of responsibilities with a high degree of flexibility to adapt to company and industry changes.
- Collaborative leader able to operate effectively and with a strong sense of urgency in a fast-paced environment.
- Organized problem solving and troubleshooting skills (e.g. rational progression of investigation).
- Comfortable challenging the status quo and bringing forward innovative solutions to make better possible.
- Proficient at creating and communicating a clear vision among team members effectively aligning resources and activities to achieve functional area and/or organizational goals.
- Excellent documentation skills (e.g. notebook, reports).
- Outstanding communicator: direct, effective, clear, concise, well organized and appropriate. (e.g. able to participate in scientific discussions and written interactions).
Work Environment:
The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodation may be made to enable individuals with disabilities to perform the essential functions. This may be a remote position with some visitations of laboratory settings.
Benefits:
- Medical, Prescription, Dental, Vision Coverage
- Flexible Spending Account & Health Savings Account with Company match
- Employee Assistance Program
- Mental Health Resources
- Disability Coverage
- Life insurance
- Critical Illness and Accident Insurance
- Legal and Identity Theft Protection
- Pet Insurance
- Fertility and Maternity Assistance
- 401(k) with company match
- Flexible Time Off (FTO) and 11 paid holidays
- Paid Parental Leave
-
Principal Scientist, Analytical Development
1 month ago
Boston, United States Vertex Pharmaceuticals Full timeJob Description General Summary: Vertex is seeking an experienced scientist eager to help develop both cutting-edge small molecule pharmaceuticals and the science underpinning the analytical control of their syntheses. As a member of the Analytical Development team this role will support drug development programs at Vertex with a focus on Drug...
-
Principal Scientist, Analytical Development
4 weeks ago
Boston, United States Vertex Pharmaceuticals Incorporated Full timeJob DescriptionGeneral Summary:Vertex is seeking an experienced scientist eager to help develop both cutting-edge small molecule pharmaceuticals and the science underpinning the analytical control of their syntheses. As a member of the Analytical Development team, this role will support drug development programs at Vertex with a focus on Drug Substance...
-
Principal Scientist, Formulation Development
3 weeks ago
Boston, United States Tbwa ChiatDay Inc Full timePrincipal Scientist, Formulation Development (Hybrid/Boston)About Apogee TherapeuticsFounded in 2022, Apogee Therapeutics, Inc. (Ticker: APGE) is a well-funded, Nasdaq listed company that offers the opportunity to work in a fast-paced, highly dynamic environment. We are a biotechnology company seeking to develop differentiated biologics for the treatment of...
-
Principal Data Scientist
3 days ago
Boston, United States Wood Mackenzie Full timeIn the middle of the energy transition, businesses and governments are faced with significant challenges. But the pace and scale of change mean every decision is made under mounting pressure. Now, more than ever, companies need reliable data, analytics and actionable insight. Wood Mackenzie is the leading global provider of data and analytics solutions for...
-
Principal Scientist, Analytical Development
3 weeks ago
Boston, United States Pacira BioSciences, Inc. Full timeAbout PaciraPacira BioSciences, Inc. is a leading provider of non-opioid pain management and regenerative health solutions dedicated to improving outcomes for health care practitioners and their patients. Our in-depth knowledge of non-opioid pain management, coupled with our passion for advancing patient care, drives our commitment to providing solutions...
-
Principal AI Scientist
1 month ago
Boston, United States Pristine Infotech Full timePrincipal AI Scientist Location: Boston Role: Principal AI ScientistExperience: 3 to 5 yearsQualification: PhD in AI, Comp Science, Math or Stats from exceptional institutions Can you architect real-time optimized recommendation engines leveraging cognitive, prescriptive, explainable AI? Can you develop self-learning models? Can you envision automating...
-
Principal Scientist, Analytical Development
2 days ago
Boston, MA, United States Pacira BioSciences, Inc. Full timeAbout Pacira Pacira BioSciences, Inc. is a leading provider of non-opioid pain management and regenerative health solutions dedicated to improving outcomes for health care practitioners and their patients. Our in-depth knowledge of non-opioid pain management, coupled with our passion for advancing patient care, drives our commitment to providing solutions...
-
AI Principal Data Scientist
2 weeks ago
Boston, United States Wood Mackenzie Full timeIn the middle of the energy transition, businesses and governments are faced with significant challenges. But the pace and scale of change mean every decision is made under mounting pressure. Now, more than ever, companies need reliable data, analytics and actionable insight. Wood Mackenzie is the leading global provider of data and analytics solutions for...
-
Senior Scientist
4 weeks ago
Boston, United States Takeda Pharmaceutical Full timeBy clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job...
-
Principal Scientist
1 week ago
Boston, United States Tbwa ChiatDay Inc Full timeLocation: This position may be performed remotely with travel to the Boston area as needed.The OpportunityWe’re seeking a Principal Scientist of Process Chemistry to lead drug substance activities for one or more projects within Praxis’ portfolio to support clinical and commercial supply. Apply your knowledge to design products & processes to support...
-
Principal Scientist
2 weeks ago
Boston, United States Tbwa ChiatDay Inc Full timeLocation: This position may be performed remotely with travel to the Boston area as needed.The OpportunityWe’re seeking a Principal Scientist of Process Chemistry to lead drug substance activities for one or more projects within Praxis’ portfolio to support clinical and commercial supply. Apply your knowledge to design products & processes to support...
-
Boston, United States Tbwa ChiatDay Inc Full timePrincipal Associate Scientist, LNP DiscoveryCompany Overview:Strand Therapeutics is a clinical stage biotechnology company utilizing synthetic biology to genetically program mRNA to deliver truly revolutionary immunotherapies to patients.Building on the idea of creating smart therapies based on Boolean logic circuits, Strand was started by biological...
-
Boston, United States Dewpoint Therapeutics Full timeDewpoint Therapeutics translates condensate biology into much-needed medicines. Biomolecular condensates are transforming our understanding of biology, and our highly collaborative team is at the forefront of efforts to harness this shift for drug discovery. Together, we are leveraging this transformation in understanding of cellular biology to discover and...
-
Boston, United States Society of Exploration Geophysicists Full timeDewpoint Therapeutics translates condensate biology into much-needed medicines. Biomolecular condensates are transforming our understanding of biology, and our highly collaborative team is at the forefront of efforts to harness this shift for drug discovery. Together, we are leveraging this transformation in understanding of cellular biology to discover and...
-
Principal Quant Developer
1 week ago
Boston, United States Selby Jennings Full timeOverview:We are seeking a highly skilled Principal Quantitative Developer to join our Boston-based team at a leading global asset management firm. This individual will play a critical role in designing, developing, and optimizing quantitative investment models and strategies while driving the evolution of our quantitative research and development...
-
Boston, United States Softbank Investment advisers Full timeAbout Dewpoint TherapeuticsDewpoint is the first company to apply the emerging understanding of biomolecular condensates to drug discovery.Job DescriptionDewpoint Therapeutics translates condensate biology into much-needed medicines. Biomolecular condensates are transforming our understanding of biology, and our highly collaborative team is at the forefront...
-
Boston, United States Dewpoint Therapeutics Full timeDewpoint Therapeutics translates condensate biology into much-needed medicines. Biomolecular condensates are transforming our understanding of biology, and our highly collaborative team is at the forefront of efforts to harness this shift for drug discovery. Together, we are leveraging this transformation in understanding of cellular biology to discover and...
-
boston, United States Dewpoint Therapeutics Full timeDewpoint Therapeutics translates condensate biology into much-needed medicines. Biomolecular condensates are transforming our understanding of biology, and our highly collaborative team is at the forefront of efforts to harness this shift for drug discovery. Together, we are leveraging this transformation in understanding of cellular biology to discover and...
-
Boston, United States Dewpoint Therapeutics Full timeDewpoint Therapeutics translates condensate biology into much-needed medicines. Biomolecular condensates are transforming our understanding of biology, and our highly collaborative team is at the forefront of efforts to harness this shift for drug discovery. Together, we are leveraging this transformation in understanding of cellular biology to discover and...
-
Boston, United States Selby Jennings Full timePrincipal Quant Developer Selby Jennings Boston, United States Apply now Posted 3 days ago Hybrid Job Permanent Negotiable Overview: We are seeking a highly skilled Principal Quantitative Developer to join our Boston-based team at a leading global asset management firm. This individual will play a critical role in designing, developing, and optimizing...
