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Senior Scientist I

4 months ago

Franklin, United States B2S Life Sciences LLC Full time
Job DescriptionJob DescriptionDescription:

The Senior Scientist - Bioanalytical Method Development is a part of the Assay Development team which designs and executes assays that complement the company's capabilities in custom critical reagents to enable clients to efficiently make data-driven decisions for optimal analytical outcomes to support biotherapeutic drug development. To realize this goal, B2S offers a range of services from drug discovery through nonclinical/clinical development. This includes early phase ADME investigations, reagent optimization, generation of optimal matched pair of antibodies, method qualification, and non-GLP sample analysis.


The Senior Scientist develops, documents, and qualifies large molecule bioanalytical methods including, but not limited to PK/TK, immunogenicity, and biomarker assays to support a range of nonclinical/clinical studies. The Senior Scientist will:


  • Design and develop new bioanalytical methods primarily based on ligand binding assays to support the development of large molecule therapeutics.
  • Perform a variety of assays including conventional Enzyme Linked Immuno Sorbent Assay (ELISA)/Electrochemiluminescence (ELISA/ECL) immunoassays as well as biophysical/biochemical/bioanalytical characterization techniques including bio-layer interferometry.
  • Complete sample analysis and method qualifications.
  • Troubleshoot existing analytical methods.
  • Review data associated with method investigations, development, and qualification efforts.
  • Compile scientific data (including analysis and technical writing) in an intelligible format suitable for a professional audience
  • Record and note the experimental processes on time and in a correct documentation format.
  • Report and treat data with high level of integrity and ethics.
  • Comply with application able regulations (GXP); maintain proper records in accordance with standard operating procedures (SOPs) and policies; independently design and perform scientific experiments with a pre-defined goal including developing new methodologies, protocols, and/or test procedures that contribute to core group research goals and reflect expert knowledge.
  • Write, edit, and revise standard operating procedures (SOPs), qualifications, and forms.
  • Independently apply basic scientific principles, perform literature searches, attend scientific meetings, and keep up to date on literature in the biotherapeutic bioanalysis field.
  • Order laboratory supplies, as needed.
  • Maintain laboratory equipment, as needed.
  • Perform other duties as assigned.
Requirements:

Education and Experience:

The ideal candidate will have a Bachelor’s Degree (B.S.) with at least five-years of direct laboratory experience, or a Master’s Degree (M.S.) in chemistry or a related science with at least three-years of direct laboratory experience. An equivalent combination of related education and required work experience will be considered with management approval.

ELISA/Ligand Binding Assay experience strongly preferred


Incumbent must have the ability to adapt and conform to shifting priorities and demands and execute accordingly. Strong organizational, and communication skills, both written and verbal are required. The position may require some evening and weekend work, domestic travel and a valid driver’s license. Computer software skills required including Microsoft Office Suites.


Physical Demands:

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential duties and responsibilities.

While performing the duties of this job, the employee is regularly required to sit; stand; walk; use hands to finger, handle, or feel; and talk or hear. The employee is occasionally required to reach with hands and arms; taste or smell; and lift and/or move up to 25 pounds.


Work Environment:

The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential duties and responsibilities. While performing the duties of this job, the employee may be regularly exposed to vibration; and the risk of electrical shock when working with Company-owned equipment. The employee may occasionally work near moving mechanical parts; and be exposed to toxic or caustic chemicals. The noise level in the work environment is usually quiet to moderate.

Personal protective equipment must be worn as required if in the laboratory to include closed-toed shoes, laboratory coat, safety goggles, and gloves.


Company Benefits:

  • Medical
  • FREE Dental, & Vision Insurance
  • 401(k) Plan
  • Company Provided Life Insurance
  • Voluntary Life Insurance
  • Employee Assistance Program (EAP)
  • 100% Paid Parental Leave
  • 100% Paid Medical Leave
  • Service Awards
  • Professional Development
  • Paid Vacation, Holidays, Bereavement, Sick and Personal Days
  • Paid Volunteer Hours
  • Company Sponsored Events

About B2S Life Sciences

B2S Life Sciences provides employees with the opportunity to make a meaningful impact by enabling excellence in biotherapeutics.


B2S Life Sciences LLC is a partnership-focused biotherapeutic enablement company located in Franklin, Indiana. Our team creates value through specialization in bioanalytical consulting, immunoassay development, custom biological reagent generation and life-cycle management (LCM), immunogenicity cut point analysis, PK/TK statistics and advanced analytics. Ultimately, we work with clients to enable the advancement of human health outcomes for a variety of disease states and chronic conditions and are driven by creating mutual success toward a common goal.


B2S Life Sciences offers excellent full-time benefits including comprehensive medical coverage, dental and vision plans, life and disability insurance, 401(k) with company match, and paid time off.


It is the Company’s policy to afford equal employment and advancement opportunity for all qualified individuals without distinction or discrimination because of race, national origin, religion, age, color, sex, sexual orientation, gender identity, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.