Principal PBPK Consultant

7 days ago

Wayne, United States Certara USA, Inc. Full time
Job DescriptionOverview

About Certara

Certara accelerates medicines using proprietary biosimulation software, technology and services to transform traditional drug discovery and development. Its clients include more than 2,000 biopharmaceutical companies, academic institutions, and regulatory agencies across 62 countries

Certara accelerates medicines using proprietary biosimulation software, technology and services to transform traditional drug discovery and development. Its clients include more than 2,000 biopharmaceutical companies, academic institutions and regulatory agencies across 62 countries.

In the past 6 years, over 90% of companies that received new drug approvals by the FDA used our software or services. Together with our partners, we use biosimulation and technology-enabled services to transform drug discovery and development across all therapeutic areas and innovative therapies.

The Certara Predictive Technologies PBPK consultancy team is a global organisation focussed on using the Simcyp physiologically-based pharmacokinetic (PBPK) platform to influence decision making on drug development programs from discovery to regulatory filing. Our PBPK consultants work with 100s of clients to inform human PK prediction, drug-drug interaction assessment, special population predictions and biopharmaceutics strategy.


We are seeking highly motivated and talented PBPK modelling scientists and experts with a DMPK, PBPK and/or a biopharmaceutics modelling background who share our passion for using PBPK models to understand and impact drug discovery and development questions.

The successful candidate will join an internationally recognised, multidisciplinary company, providing opportunities for further development of knowledge and skills. We offer a unique and exciting mix of academic and commercial environments which encourage regular attendance at scientific meetings as part of our continuous education programmes. The post does not include routine laboratory or clinical work.


Responsibilities

The role involves contributing to consultancy projects with clients in the Pharmaceutical Industry to develop PBPK models for particular projects of interest.
Apply PBPK models in support of a number of applications including but not limited to the following:

  • DDI liability prediction;
  • Food effect prediction
  • PK prediction in special populations
  • Biopharmaceutics/bioequivalence prediction
  • Large molecule PK prediction.
  • You will be expected to contribute to consultancy projects with supervision.
  • You will need to keep abreast of the latest scientific development in the area of PBPK and IVIVE to enable effective communication with colleagues, clients and the wider scientific community.

Qualifications

  • A PhD degree in a relevant field or equivalent experience in the field of IVIVE/ drug metabolism/ pharmacokinetics.
  • Should have some knowledge of the application of PBPK modelling in the drug discovery and development process.
  • Has knowledge and understanding of IVIVE/ drug metabolism/ pharmacokinetics.
  • Should have a sound overview of the simulator with good knowledge and understanding of specific areas.
  • Excellent communication skills to effectively engage with peers and clients within industry, academia and regulatory agencies.

Certara bases all employment-related decision on merit, taking into consideration qualifications, skills, achievement, and performance. We treat all applicants and employees without regard to personal characteristics such as race, color, ethnicity, religion, sex, sexual orientation, age, nationality, marital status, pregnancy, physical or mental condition, genetic information, military service, or other characteristic protected by law.

RequiredPreferredJob Industries
  • Other

  • Principal PBPK Consultant

    7 days ago

    Wayne, PA, United States Certara USA, Inc. Full time

    OverviewAbout CertaraCertara accelerates medicines using proprietary biosimulation software, technology and services to transform traditional drug discovery and development. Its clients include more than 2,000 biopharmaceutical companies, academic institutions, and regulatory agencies across 62 countriesCertara accelerates medicines using proprietary...

  • Senior PBPK Consultant

    7 days ago

    Wayne, United States Certara USA, Inc. Full time

    Job DescriptionOverviewAbout CertaraCertara accelerates medicines using proprietary biosimulation software, technology and services to transform traditional drug discovery and development. Its clients include more than 2,000 biopharmaceutical companies, academic institutions and regulatory agencies across 62 countries.In the past 6 years, over 90% of...

  • Senior PBPK Consultant

    7 days ago

    Wayne, United States Certara USA, Inc. Full time

    OverviewAbout CertaraCertara accelerates medicines using proprietary biosimulation software, technology and services to transform traditional drug discovery and development. Its clients include more than 2,000 biopharmaceutical companies, academic institutions and regulatory agencies across 62 countries. In the past 6 years, over 90% of companies that...

  • Senior PBPK Consultant

    8 hours ago

    Wayne, United States Certara USA, Inc. Full time

    OverviewAbout CertaraCertara accelerates medicines using proprietary biosimulation software, technology and services to transform traditional drug discovery and development. Its clients include more than 2,000 biopharmaceutical companies, academic institutions and regulatory agencies across 62 countries. In the past 6 years, over 90% of companies that...

  • Senior Director PBPK Consultancy

    7 days ago

    Wayne, United States Certara USA, Inc. Full time

    Job DescriptionOverviewAbout CertaraCertara accelerates medicines using proprietary biosimulation software, technology and services to transform traditional drug discovery and development. Its clients include more than 2,000 biopharmaceutical companies, academic institutions and regulatory agencies across 62 countries.The Certara Simcyp PBPK consultancy team...

  • Senior PBPK Consultant

    3 days ago

    Wayne, PA, United States Certara USA, Inc. Full time

    Overview About Certara Certara accelerates medicines using proprietary biosimulation software, technology and services to transform traditional drug discovery and development. Its clients include more than 2,000 biopharmaceutical companies, academic institutions and regulatory agencies across 62 countries. In the past 6 years, over 90% of companies...

  • Senior Director PBPK Consultancy

    7 days ago

    Wayne, PA, United States Certara USA, Inc. Full time

    OverviewAbout CertaraCertara accelerates medicines using proprietary biosimulation software, technology and services to transform traditional drug discovery and development. Its clients include more than 2,000 biopharmaceutical companies, academic institutions and regulatory agencies across 62 countries. The Certara Simcyp PBPK consultancy team is a global...

  • Senior Director PBPK Consultancy

    1 day ago

    Wayne, PA, United States Certara USA, Inc. Full time

    OverviewAbout CertaraCertara accelerates medicines using proprietary biosimulation software, technology and services to transform traditional drug discovery and development. Its clients include more than 2,000 biopharmaceutical companies, academic institutions and regulatory agencies across 62 countries. The Certara Simcyp PBPK consultancy team is a global...

  • Implementation Consultant

    3 months ago

    Wayne, United States AssetWorks Inc Full time

    Job Summary:The Implementation Consultant will focus on a broad range of software implementation activities, working primarily with external customers but also with internal departments such as product development, quality assurance and customer care. The ideal candidate will have established experience in a similar professional services environment,...

  • Scientist

    2 weeks ago

    Wayne, United States Certara USA, Inc. Full time

    OverviewAbout Certara Certara is a growing company that provides a dynamic and exciting place to work. Our purpose is to assist in accelerating the development of meaningful medicines that make an impact on our society and the people that need them most. Innovation and creativity are highly valued, and everyone is given the opportunity for training and...

  • Scientist, QSP

    7 days ago

    Wayne, United States Certara USA, Inc. Full time

    Job DescriptionOverviewAbout CertaraCertara is a growing company that provides a dynamic and exciting place to work. Our purpose is to assist in accelerating the development of meaningful medicines that make an impact on our society and the people that need them most. Innovation and creativity are highly valued, and everyone is given the opportunity for...

  • Scientist, QSP

    7 days ago

    Wayne, United States Certara USA, Inc. Full time

    OverviewAbout Certara Certara is a growing company that provides a dynamic and exciting place to work. Our purpose is to assist in accelerating the development of meaningful medicines that make an impact on our society and the people that need them most. Innovation and creativity are highly valued, and everyone is given the opportunity for training and...

  • Principal - Supply Chain Program Management

    1 month ago

    Fort Wayne, United States Ohm Systems, Inc Full time $130,000 - $160,000

    Summary: The Supply Chain Program Manager for Space Systems will lead and manage supply chain program initiatives for responsive space programs, focusing on technology development and mission solutions. This role requires collaboration with engineering, operations, and suppliers to ensure optimal program execution, supplier performance, and alignment with...

  • Scientist, QSP

    7 days ago

    Wayne, PA, United States Certara USA, Inc. Full time

    OverviewAbout Certara Certara is a growing company that provides a dynamic and exciting place to work. Our purpose is to assist in accelerating the development of meaningful medicines that make an impact on our society and the people that need them most. Innovation and creativity are highly valued, and everyone is given the opportunity for training and...

  • Covenant House Academy

    2 days ago

    Wayne, United States Wayne County Schools Employment Network Full time

    Position Type: Special Education/Speech and Language Pathologist Date Posted: 12/9/2024 Location: Covenant Schools (High-Needs School) District: Covenant House Academy Central (District) Speech and Language PathologistSalary Range: $75-$90 per hour, dependent upon certifications and experience. Reports to: Principal Schedule: Part-time, 16-24 hours per...

  • Software Test Engineer

    3 days ago

    Fort Wayne, United States Actalent Full time

    Description The Software Test Engineer roles will be a part of the Test Engineering group who are responsible for developing new PXI Test Stands for UTEC's electronic products. Will be responsible for the following: writing test programs in C# reviewing and analyzing current test shells in ANSI C (LabWindows CVI) and VB.net modifying exisiting code to...

  • Nurse

    1 month ago

    Fort Wayne, United States Northwest Allen County Schools Full time

    Position Type: School Support Staff Date Posted: 8/28/2024 Location: Carroll High School NORTHWEST ALLEN COUNTY SCHOOLS Job Description Position: PK-12 School Nurse Supervisor: Corporation Nurse, Principal Duties and Responsibilities: The school nurse is often the only health care provider in the school setting; therefore school nurses may be called upon to...

  • Nurse

    1 month ago

    Fort Wayne, United States Northwest Allen County Schools Full time

    Position Type: School Support StaffDate Posted: 8/28/2024Location: Carroll High SchoolNORTHWEST ALLEN COUNTY SCHOOLS Job Description Position: PK-12 School Nurse Supervisor: Corporation Nurse, Principal Duties and Responsibilities: The school nurse is often the only health care provider in the school setting; therefore school nurses may be called upon to the...