Principal Scientist or Sr. Principal Scientist

1 day ago

New Brunswick NJ United States Cfdv Full time
Principal Scientist or Sr. Principal Scientist - Analytical Development

Primary Location: New Brunswick, New Jersey or Summit, New Jersey

We are seeking an experienced leader with strong analytical technical skills and a passion for strategic project leadership, mentoring others, and driving technical innovation to solve challenging problems. This role will provide analytical subject matter expertise and analytical leadership within process development teams consisting of organic chemists, chemical engineers, and analytical scientists to support an increasingly complex portfolio of small molecules and milla-molecular (ADCs, peptides, oligonucleotides) drug candidates from phase 1 to commercialization. The successful candidate is expected to manage multiple projects, provide strategic leadership, and collaborate with stakeholders to move the portfolio through development to regulatory submissions.

Overall responsibilities of this role may include:

  1. Coordinating the analytical activities in alignment with other project leads (process chemistry, engineering, technology, and supply) to enable process innovation and invention.
  2. Developing phase appropriate analytical control strategies and coordinating method development, validation, and transfer activities to support process development, internal/external campaigns, compliance needs, and regulatory submissions.
  3. Providing fit-for-purpose analytical methods and analyses which provide key insights and process knowledge for scale-up and process optimization studies for projects within the portfolio.
  4. Appropriate resource planning and activity coordination of internal and external work packages.
  5. Partnering with other Analytical Functions across the Product Development and Commercial organizations to integrate/align analytical strategies, build development knowledge, collect necessary analytical data, and significantly influence specification setting and IND/NDA submission content.
  6. Capability to adapt and grow within a dynamic environment including both internally and externally based development activities. Collaborate with SMEs/project team on innovative analytical approaches to solve challenging problems. Leverage technical expertise to drive problem solving and knowledge gathering.
  7. Seeking opportunities to influence/mentor other scientists in the team, the wider analytical community, or the external community (through consortia/guidance and publications) through lessons learned and workflow/practice enhancements.
  8. Accountable for identifying opportunities and/or implementing solutions to improve efficiency, productivity, and quality across various areas including: continuous processing, applying automation, screening, smart technology, and vendor interactions.

The successful candidate is expected to significantly impact the advancement of the portfolio through their strong analytical technical skills, strategic leadership, and capability to manage multiple projects at various development stages. They are expected to grow into project leadership positions of increasing responsibility including the project leader for all drug substance development activities and become a significant influencer within our wider CMC development teams. Advancement along the technical ladder is also achievable through cross-functional problem solving and technology implementation/knowledge gathering that advance the portfolio.

Qualifications/Requirements:

  1. Ph.D. or Masters in analytical, organic chemistry, or engineering is required. Proven track record and experience directly relevant to the role is critical to success. Experience in working across matrixed and/or externalized teams is highly desirable for Senior Principal Scientist position.
  2. 4+ years’ experience for Principal Scientist, and 6+ years’ experience for Senior Principal Scientist, in analytical development in the pharmaceutical industry. Experience in supporting API process development is preferred. Experience with late-stage registrational filings is a plus.
  3. Demonstrated expertise in a wide variety of analytical techniques is highly preferred.
  4. Demonstrated commitment to safety.
  5. Excellent interpersonal, time management, collaborative, team building, and communication skills are desired to ensure effective collaborations within matrix teams. Demonstrated performance against cooperation principles and enterprise mindset.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services, and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

#J-18808-Ljbffr

  • Principal Scientist/Senior Principal Scientist, Form Characterization

    1 day ago

    Summit, NJ, United States Bristol-Myers Squibb Full time

    Principal Scientist/Senior Principal Scientist, Form Characterization Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the...

  • Principal Scientist

    1 day ago

    Bridgewater Township, NJ, United States Nestlé SA Full time

    Principal Innovation Sensory Insights Scientist At Nestlé Health Science, we believe that nutrition, science, and wellness must merge, not collide. Here, we embrace the intrinsic connections of these three pillars, harnessing their collective strength to empower healthier lives. Our broad product portfolio includes renowned brands like Garden of Life,...

  • Principal AI Scientist

    1 day ago

    Denver, CO, United States Altamira Technologies Corp. Full time

    Altamira Technologies is seeking a Principal AI Scientist that possesses a mix of talent related to artificial intelligence / machine learning, data science, and traditional algorithms. In response to emergent customer requirements, the Principal AI Scientist leverages their understanding of national security missions to develop innovative and viable...

  • Sr. Principal Applied Scientist, Sponsored Products, Advertiser Growth

    8 hours ago

    Seattle, WA, United States Amazon Full time

    Sr. Principal Applied Scientist, Sponsored Products, Advertiser Growth Job ID: 2785228 | Amazon Advertising LLC The Sponsored Products (SP) team is looking for a Sr. Principal Scientist to help our millions of advertisers create, manage and optimize their campaigns with improved recommendations to drive efficient advertising sales. Amazon Advertising is one...

  • R&D Sr. Principal

    8 hours ago

    Linthicum, MD, United States Associates Systems LLC Full time

    Our company pushes the boundaries of innovation, redefines the leading edge of exotic new technologies, and drives advances in the sciences. One of our most challenging new fields is Transformational Computing, which combines the unique properties of superconductivity and quantum mechanics to develop radical new energy-efficient computing systems. Our team...

  • Principal Scientist

    8 hours ago

    Woburn, MA, United States Spear Bio Inc. Full time

    Spear Bio is a well-funded and rapidly growing start-up company based in Woburn, Massachusetts. We are focused on bringing to market a novel ultrasensitive immunoassay platform utilizing very small sample volumes. The commercial focus of the company is dedicated to supporting life sciences, clinical, and academic research. Our platform offers best-in-class...

  • Principal Scientist, MAPS

    5 hours ago

    Cambridge, MA, United States GlaxoSmithKline Full time

    Site Name: USA - Massachusetts - CambridgePosted Date: Dec 4 2024The Principal Scientist, MAPS will be a part of the Process Development group under Technical R&D. The Principal Scientist is expected to design and execute scientific studies in support of technical programs as they progress from early development into Phase I/ II, Phase III, technology...

  • Principal Health Scientist

    1 day ago

    Newton, MA, United States Energy Jobline AZ Full time

    Principal Scientist Summary: Principal Scientists direct or manage projects with potentially high stakes, requiring thoughtful application of the appropriate technical disciplines and professional judgment. They oversee the scope and quality of service delivery from the beginning to the end of a project, by ensuring that the team is aware of, and addresses...

  • Principal Applied Scientist

    3 months ago

    New York, United States McGregor Boyall Full time

    Principal Applied ScientistRole:We are seeking a highly skilled Principal Applied Scientist to join a leading quantitative investment team. The successful candidate will play a pivotal role in developing and applying advanced machine learning and statistical models to drive alpha generation, including the application of cutting-edge LLMs and Generative AI...

  • Principal Applied Scientist

    2 days ago

    New York, United States Amazon Full time

    Principal Applied Scientist, Responsible AI Job ID: 2593405 | Amazon Development Center U.S., Inc. At AWS, we build and operate AI services responsibly, driving measurable success along multiple Responsible AI dimensions, including safety, fairness, privacy, security, robustness, explainability, and transparency. As a Principal Applied Scientist on this...

  • Principal Scientist

    9 hours ago

    Coventry, RI, United States Pharmaron Beijing Co. Ltd. Full time

    We are seeking a Principal Scientist to join our team in Coventry, RI. The Principal Scientist, Analytical will spearhead manufacturing and process chemistry activities through the development, optimization, validation, and transfer of analytical methods, adhering to all relevant guidelines. Primary Responsibilities: Execute all tasks promptly and...

  • Principal Scientist- Global Regulatory Affairs-CMCS

    8 hours ago

    , MS, United States Firefingrill Full time

    Position: Principal Scientist - Global Regulatory Affairs-CMC Purpose: The Principal Scientist-Global Regulatory Affairs-CMC role aims to provide strategic, tactical, and operational direction to expedite CMC development and technical agendas by supporting global clinical trial, market registration submissions, and post-approval submissions. This is...

  • Principal Scientist, Analytical Development

    1 day ago

    Cambridge, MA, United States Apex Systems Full time

    Principal Scientist, Analytical Development Location : Cambridge, MA (Onsite)Science: Small Molecule Therapeutics Job Overview: The Principal Scientist in Analytical Development guides pharmaceutical advancements from inception through clinical stages and collaborates with internal and external partners. Primary Job Responsibilities: Develop specialized...

  • Principal Applied Scientist

    2 months ago

    new york city, United States McGregor Boyall Full time

    Principal Applied ScientistRole:We are seeking a highly skilled Principal Applied Scientist to join a leading quantitative investment team. The successful candidate will play a pivotal role in developing and applying advanced machine learning and statistical models to drive alpha generation, including the application of cutting-edge LLMs and Generative AI...

  • Principal Applied Scientist

    3 months ago

    new york city, United States McGregor Boyall Full time

    Principal Applied ScientistRole:We are seeking a highly skilled Principal Applied Scientist to join a leading quantitative investment team. The successful candidate will play a pivotal role in developing and applying advanced machine learning and statistical models to drive alpha generation, including the application of cutting-edge LLMs and Generative AI...

  • Principal Data Scientist

    1 day ago

    Richmond, VA, United States Capital One Full time

    Locations: VA - McLean, United States of America, McLean, Virginia Principal Data Scientist Principal Data Scientist – Consumer Credit Risk Management Models and Data Data is at the center of everything we do. As a startup, we disrupted the credit card industry by individually personalizing every credit card offer using statistical modeling and the...

  • Principal Scientist, ADC Characterization

    4 weeks ago

    Boulder, CO, United States SciPro Full time

    SciPro is excited to share an extraordinary opportunity with our key client in Colorado who is seeking a Principal Scientist, ADC/Antibody Characterization to join their innovative team.This is not just another role—our client is backed by a former C-Suite executive from one of the largest global software companies, and they are at the forefront of...

  • Principal Scientist, Biotransformation

    1 day ago

    Indianapolis, IN, United States IQVIA Laboratories Full time

    We are seeking a Principal Scientist, Biotransformation to join IQVIA Laboratories business in Indianapolis, IN . We hire passionate innovators who drive healthcare forward through thoughtful and inclusive collaboration. If you want to discover a career with greater purpose, join us as we transform and accelerate research and development. As a Principal...

  • Principal Scientist Bioanalytical

    4 weeks ago

    Frederick, MD, United States Mackinnon Bruce International Full time

    We are working alongside our client in the Contract Clinical Research sector based in Maryland to hire a Principal Scientist (Bioanalytical).Who we areWe are a dynamic recruitment agency that has evolved since our first establishment in 2012. We work with several high-profile clients globally to help them source and retain top-tier talent. The clientOur...

  • Principal Material Scientist

    4 weeks ago

    Westwood, MA, United States enVerid Systems, Inc. Full time

    Position: Principal Material ScientistManager: Alex Goodwin, SVP Product and EngineeringLocation: Westwood, MA (Onsite)About the Company enVerid Systems is a leader in indoor air quality and energy efficiency for commercial buildings. Our Sorbent Ventilation Technology™ (SVT) improves indoor air quality, lowers a building’s carbon footprint, and reduces...