Senior Scientist, External Programs Lab Science San Mateo, CA

2 days ago


San Mateo CA United States BigHat Full time
Senior Scientist, External Programs

Department: Lab Science

Employment Type: Full Time

Location: San Mateo, CA


Description

The Role: BigHat Biosciences is seeking an exceptional individual for a Senior Scientist on the External Programs team to serve as a program team lead and drive antibody design, discovery, optimization and characterization, in support of therapeutic programs with our external partners.

This role reports directly to Emily Delaney, Sr. Scientist II, External Programs.


Key Responsibilities
  • Lead cross-functional project teams (including Data Science, AI/ML, Engineering, Protein Sciences, Automation) on the execution of rapid, iterative multi-objective optimization to identify high-value therapeutic antibodies through gold-standard assays.
  • Effectively and regularly synthesize and communicate results and research activity to key decision makers and the broader BigHat team, as well as to external partners.
  • Collaborate closely with BigHat leadership and other cross-functional team members to ensure a tight linkage between strategy, research, and development components.
  • Develop strategies to generate and optimize novel antibodies that meet and exceed design requirements, as set forth in BigHat’s collaborative external partnerships.
  • Source, onboard, develop, and validate bespoke assays to assess in vitro cell-based functional activity of therapeutic antibody candidates.
  • Deeply understanding target biology to better design antibodies that meet our candidate profile
  • Lead a team in-depth data analysis of each design cycle to better leverage experimental and computational approaches to reach our design goals

Skills Knowledge and Expertise
  • Ph.D. in molecular or cell biology, immunology, or related fields.
  • 3+ years of advanced research experience in an industry setting.
  • Experience with antibody engineering and/or discovery.
  • Exceptional written, verbal and visual communication skills.
  • Experience presenting and communicating strategy and results to internal and external partners.
  • Experience leading direct reports and teams.
  • Experience in leading cross-functional project teams, including planning timelines, adhering to budgets, presenting interim key results internally and externally, is a plus.
  • Strong scientific track record and publication record.
  • Strong data analysis and interpretation skills. Experience working with large datasets.
  • Expertise in mammalian cell culture, immunoassay, molecular techniques, cell-based assays, protein expression and characterization (e.g., kinetics, SEC).
  • Experience with lab automation is a plus.
  • If you love asking questions, tinkering, and diving headfirst into diverse, highly technical projects BigHat could be the right home for you.
#J-18808-Ljbffr

  • San Mateo, California, United States County of San Mateo, CA Full time

    The County of San Mateo, CA is seeking a highly qualified Dentist Supervisor to join our team at the San Mateo Medical Center. As a key member of our dental services program, you will be responsible for supervising and directing the work of assigned staff, including professional, paraprofessional, and support personnel.Job OverviewWe are looking for an...


  • San Mateo, CA, United States MIT RESOURCE Full time

    Data Science Engineer permanent position at San Mateo, CA Full-time Title: Data Science Engineer Location: San Mateo, CA Type: permanent Job Description: Client is a leader in applying Big Data technology to extract and analyze unstructured and coded clinical data to derive outcome- and cost-related insights. Based in Silicon Valley, client offers...


  • San Mateo, California, United States County of San Mateo, CA Full time

    About the RoleWe are seeking a highly skilled and experienced Medical Director of Adult Psychiatry to join our team at San Mateo Medical Center. As a key member of our healthcare team, you will be responsible for providing clinical and administrative leadership in the Department of Psychiatry.ResponsibilitiesDirect and administer an adult psychiatric program...


  • San Mateo, California, United States County of San Mateo (CA) Full time

    We are looking for a highly skilled Licensed Vocational Nurse to join our team at the San Mateo Medical Center. As a LVN, you will play a critical role in providing quality patient care and contributing to the success of our healthcare team.Job Summary:This position offers a unique opportunity to work in a fast-paced and challenging environment. You will...


  • San Mateo, California, United States Home Helpers San Mateo Full time

    OverviewWe are a 9-year 'Employer of Choice' and one of the fastest-growing and most respected agencies in San Mateo County. Our award-winning company has a culture built around kindness, respecting your time with flexible schedules.You will find deep purpose in a job that often doesn't feel so much like a work when working for us.


  • San Mateo, United States Sunbelt Staffing Full time

    Job DescriptionJob DescriptionMinimum 1+ years Behavior Specialist experience required.Sunbelt is hiring an experiencedBehavior Techniciannear San Mateo, CA, area for the upcoming school year!Qualifications:Experience working within a schoolExperience working students withsevere disabilitiesCPR/CPI CertificationJob details:On-site near San Mateo,...


  • San Mateo, United States Sunbelt Staffing Full time

    Job DescriptionJob DescriptionMinimum 1+ years Behavior Specialist experience required.Sunbelt is hiring an experiencedBehavior Techniciannear San Mateo, CA, area for the upcoming school year!Qualifications:Experience working within a schoolExperience working students withsevere disabilitiesCPR/CPI CertificationJob details:On-site near San Mateo,...


  • San Mateo, California, United States County of San Mateo (CA) Full time

    Job OverviewThe County of San Mateo is seeking a full-time extra help Environmental Educator to join the Interpretive Division.About the JobThis position will be employed from January 2025 to December 2025 and requires regular work at various San Mateo County Parks, including Fitzgerald Marine Reserve, San Pedro Valley Park, Coyote Point Recreation Area, and...

  • Public Health Nurse

    3 weeks ago


    San Mateo, United States County of San Mateo (CA) Full time

    San Mateo County Health is seeking an experienced and well-qualified limited term Public Health Nurse - Communicable Disease Control Program. The mission of the Communicable Disease Control Program is to protect and promote the health of all County of San Mateo residents through surveillance, investigation, prevention and control of communicable diseases...


  • San Mateo, California, United States San Mateo Community College District Full time

    The San Mateo County Community College District is committed to achieving educational equity for all students. As outlined in the District's Strategic Plan, "success, equity, and social justice for our students are longstanding goals."We provide students with a rich and dynamic learning experience that embraces differences - emphasizing collaboration and...


  • San Mateo, United States Home Helpers San Mateo Full time

    Benefits: Daily pay via Tapcheck - yes, we can pay you every day you work!Full medical, dental, and vision benefits for full-time employees$150 sign-on bonus, after working 30 shifts$300 Referral Bonus offered to hourly caregiversPaid Training - Initially and OngoingPaid Sick LeaveHome Helpers is looking for Exceptional Caregivers with starting pay...


  • San Mateo, United States Herewith Caregivers Full time

    About this job: We are looking for a compassionate, professional in-home caregiver to provide non-medical senior care and companionship for a 74yrs old male in San Mateo, CA. Schedule: MWF (flexible) 8-10 AM or 9-11 AM, then evening shift 6-8 PM; can increase to 5-6 days a week. Pay rate: $25-27 per hour We're looking for help with: Cooking meals and...

  • PT = HH

    2 months ago


    San Mateo, CA, United States Prime HealthCare Staffing Full time

    This will be a home health position for the San Francisco/San Mateo CA area. Visits will vary on a weekly basis, but will be guaranteed 40 hours a week. Mileage will be reimbursed at the government rate.This position will start mid August for 13 weeks, 8 hours a day, Monday thru Friday. If interested, please call me at x 088, or email me at as well.Prime...

  • PT = HH

    3 months ago


    San Mateo, CA, United States Prime HealthCare Staffing Full time

    This will be a home health position for the San Francisco/San Mateo CA area. Visits will vary on a weekly basis, but will be guaranteed 40 hours a week. Mileage will be reimbursed at the government rate.This position will start mid August for 13 weeks, 8 hours a day, Monday thru Friday. If interested, please call me at x 088, or email me at as well.Prime...


  • San Mateo, United States Sunbelt Staffing Full time

    Job DescriptionJob DescriptionMinimum 1+ years special education experience required.Full Time Special Education Teacher Position - San Mateo CA Sunbelt is hiring a Special Education Teacher for a school in the San Mateo area. This position is onsite, and full-time M-F.Caseload and student disabilities vary.Job Type: - Full-Time (32.5 - 37.5 hours) - M-F -...


  • San Mateo, United States County of San Mateo (CA) Full time

    San Mateo County Health is seeking an experienced and well-qualified limited term Public Health Nurse - Communicable Disease Control Program. The mission of the Communicable Disease Control Program is to protect and promote the health of all County of San Mateo residents through surveillance, investigation, prevention and control of communicable diseases...


  • San Mateo, United States Soliant Full time

    Job DescriptionJob DescriptionMinimum 1+ years Behavior Specialist experience required.Registered Behavior Technician- San Mateo, CA Soliant Education is searching for a Registered Behavior Technicianfor a school in the San Mateo, California area! This is a full-time, onsite position forthe 2024-2025school year.About the Position:Hours:...


  • san mateo, United States The Stepping Stones Group Full time

    The Stepping Stones Group *is seeking full-time *Occupational Therapists in San Mateo, CA, to join our team in providing exceptional therapy services to students in schools. We are dedicated to helping students achieve their full potential and are looking for a passionate therapist to join us in this mission. ******* Graduate from an Occupational Therapy...


  • San Mateo, California, United States County of San Mateo, CA Full time

    Job SummaryWe are seeking a highly skilled Emergency Department Nurse Specialist to join our team at the County of San Mateo, CA. As a key member of our healthcare team, you will provide exceptional patient care and support in our Level 2 Emergency Department.

  • PT = HH

    4 weeks ago


    San Mateo, United States Prime HealthCare Staffing Full time

    This will be a home health position for the San Francisco/San Mateo CA area. Visits will vary on a weekly basis, but will be guaranteed 40 hours a week. Mileage will be reimbursed at the government rate.This position will start mid August for 13 weeks, 8 hours a day, Monday thru Friday. If interested, please call me at x 088, or email me at as well.Prime...