Director, Global Value

Job TitleVertex operates at the forefront of scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF) as well as CASGEVY, a gene therapy for sickle cell disease and beta-thalassemia, and JOURNAVX, a first-in-class treatment for moderate-to-severe acute pain. Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases including programs in B cell mediated renal diseases, APOL-1 mediated kidney disease (AMKD), chronic pain and DM-1, and cell therapies for Type 1 diabetes, among others.OverviewMarket Access is a key commercial function that ensures transformative Vertex therapies are appropriately funded and ultimately make it into the hands of the patients around the world. The GVAS (Global Value & Access Strategy) team works cross-functionally and across regions to ensure the payer view is represented in commercial and development plans across the lifecycle. We are driven by a desire to deliver groundbreaking pricing & reimbursement solutions to allow our medicines to reach patients faster than ever before.The Director, GVAS role will serve as Market Access Lead for the Hemoglobinopathies and Early Pipeline Portfolios, with a focus on lifecycle management for CASGEVY and development of an improved conditioning regimen. The Early Pipeline Portfolio is focused on bringing the next wave of innovation into the clinic and includes multiple research-stage assets in new disease areas of interest (e.g. Huntington's disease). The individual will be responsible for leading the development of Global Market Access strategies, as well as co-leading the Global Commercial Team. The role reports to Sr. Director, Hemoglobinopathies & Early Pipeline lead.Key ResponsibilitiesResponsible for Global payer strategic planning to support value and access optimization across label expansions (e.g. pediatrics)/other life cycle management considerations for CASGEVY, and an improved conditioning regimen in developmentLead development of Market Access strategies and core Global P&R deliverables, operating within the cross-functional, cross-regional commercialization processCollaborate with Health Economics & Outcomes Research (HEOR) and regional/local market access colleagues to support ongoing reimbursement/renegotiations for CASGEVY, including identification and prioritization of evidence required to optimize and sustain value over timeEnsure evidence prioritization required to capture value, support a differentiated target product profile (TPP), and ensure local pricing and access for an improved conditioning regimenAccountable for ensuring the market access and payer perspective is reflected in cross-functional strategies (e.g. commercial, product development, regulatory affairs)Support strategies with deep functional knowledge, in-depth market research, environmental data & analogsInform financial forecastsPartner with HEOR, Real-World Evidence (RWE) and Global Marketing to ensure robust value proposition and integrated evidence plans are optimized to support global market access and reimbursementCo-lead Heme Global Commercial Team (with Global Marketing) and work cross-functionally and cross-regionally to develop optimal commercial strategiesThe Global Commercial Team facilitates development of a commercial strategy to maximize the lifetime value of the asset globally; is the primary hub for alignment and input into the Disease Strategy TeamThis role should ensure collaboration and drive alignment across the Global Commercial Team and leadership to integrate market access strategy and ensure resourcing for commercial successCollaborate with cross-functional, cross-regional team to inform the commercial opportunity and clinical development/evidence considerations for early, preclinical pipeline assets and disease areas of interest; lead development of pricing and market access assessments to understand payer perspective and key implicationsSupport P&MA capability building and thought leadership projects that advance knowledge of and readiness for the rapidly evolving Global payer environmentMaintain industry awareness and proactively address changes in market trends, competition, product acceptance and new product releases and adjust Market Access plans accordinglyCollaborate closely with HEOR, regional market access, global commercial strategy, clinical development, medical affairs and corporate affairs counterparts to ensure value and access optimizationQualifications8+ years of direct biotechnology / pharmaceutical industry experience and/or payer experienceDeep working knowledge of both US and ex-US healthcare systems required; experience in comparable Global role considered a plusExperience in specialty and/or rare disease access models preferredExperience in leading cross-functional teams requiredDemonstrated ability to think strategically and make sound pricing and market access recommendationsEntrepreneurial, energetic, dynamic, enthusiastic, decisive, and self-motivated; possesses a sense of urgency with the ability and strong desire to "make things happen"Strong practical, quantitative and analytical skills combined with a sound understanding of how to successfully apply pricing & reimbursement / HEOR principles to support VertexGeneral experience in commercialization and drug developmentExhibits outstanding written and oral communication skills, including the ability to effectively write and deliver presentations to professionals at all levels within VertexDemonstrated relationship building at all levels of the organization and across geographiesRecognized as a team player with excellent interpersonal skills who is flexible and reliableDisplays sound ethics and a fit for Vertex's core valuesEducationBA/BS in field of study requiring quantitative analysis; advanced degree preferredPay Range: $201,200 - $301,800Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.Flex Designation: Hybrid-Eligible Or On-Site EligibleFlex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid : work remotely up to two days per week; or select 2. On-Site : work five days per week on-site with ad hoc flexibility.Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.Company InformationVertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com