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Director DMPK

4 months ago

Boston, Massachusetts, United States EPM Scientific Full time

We are looking for an individual who has a passion for ADME and DMPK science, applied to Cancer biology.The Drug Metabolism and Pharmacokinetics (DMPK) department provides ADME/DMPK, as well as translational PKPD Modeling & Simulation support to our portfolio.Leading DMPK-related compound design activities to ensure project ADME challenges are thoroughly assessed and resolved from HTS work-up to candidate nomination through risk mitigation and/or structural modification.Supervising and managing a team of ADME scientists by mentoring and challenging them, as well as providing expert advice and context for the interpretation of complex data.Recommending, initiating, leading and championing new innovations from external, global and local DMPK project science strategies that ensure cutting-edge science is applied to drug project issues.PhD or equivalent degree in Pharmaceutical Sciences, Molecular Biology, Chemistry, Biochemistry or Pharmacology with experience in drug discovery, or a higher degree in a research area relevant to DMPK science.At least 8+ years of relevant industry experience in ADME/Project Representation or a MS degree with at least 13+ years of relevant industry experience.Experience and knowledge of working with multiple modalities including; small molecules, biologics, nano-medicines and PROTACs is a plus.