Current jobs related to Senior Scientist - South San Francisco, California - Alector


  • South San Francisco, California, United States Amgen Full time

    About the RoleWe are seeking a highly skilled and experienced Senior Immunology Research Scientist to join our Translational Immunology and Safety Sciences group in South San Francisco, CA.As a key member of our team, you will be responsible for designing and implementing immuno-toxicological evaluation strategies, collaborating with toxicologists,...


  • South San Francisco, California, United States Amgen SA Full time

    About the RoleWe are seeking a highly skilled and experienced Senior Immunology Research Scientist to join our Translational Immunology and Safety Sciences group in South San Francisco, CA.Key ResponsibilitiesDesign and execute immuno-toxicological evaluation strategies to support pipeline projectsCollaborate with toxicologists, pathologists, and scientists...


  • San Francisco, California, United States city of San Elizario Full time

    About the RoleWe are seeking a highly skilled and experienced Senior Scientist to join our Inflammation Research team in San Elizario. As a key member of our team, you will be responsible for designing and executing experiments to explore and understand the pharmacology of drug targets, generating and communicating pharmacology and preclinical data to...


  • South San Francisco, California, United States Aequor Full time

    Position Title: Cell Culture Research Specialist / Senior Research ScientistCompany: AequorRole Overview: We are seeking a highly skilled professional to join our team as a Cell Culture Research Specialist or Senior Research Scientist. This role focuses on the development and production of Adeno-Associated Virus (AAV) for gene therapy applications.Key...


  • San Francisco, California, United States Acceler8 Talent Full time

    Acceler8 Talent Seeks Senior Data Scientist for AI InnovationAbout the Role:We are seeking a highly skilled Senior Data Scientist to lead pioneering projects in data-centric AI at Acceler8 Talent. This role offers the chance to develop cutting-edge tools that diagnose and correct dataset issues, enhancing the reliability and performance of AI models across...


  • South San Francisco, California, United States Amgen Foundation, Inc. Full time

    About the RoleWe are seeking a highly motivated and experienced Senior Research Scientist to join our Pharmacokinetics & Drug Metabolism (PKDM) department at our site in South San Francisco, California.The successful candidate will work in a team environment to characterize the absorption, distribution, metabolism, excretion and pharmacokinetic properties of...


  • South San Francisco, California, United States Biogen Full time

    Job SummaryWe are seeking a highly skilled and experienced Senior Clinical Research Scientist to join our team at Biogen. As a key member of our clinical research team, you will be responsible for leading the design, execution, and monitoring of clinical studies evaluating novel therapies across target indications.Key ResponsibilitiesLead Clinical...


  • South San Francisco, California, United States Experis Full time

    Position Overview: Our client, a prominent player in the pharmaceutical industry, is seeking aSenior Bio-conjugation Research Scientistto join their innovative team.Location: This role is based in a laboratory environment.Experience Requirements: A minimum of 8 years of relevant industry experience is essential, with a B.S./M.S. degree or 5 years of...


  • South San Francisco, California, United States Net2Source Inc. Full time

    Job SummaryWe are seeking a highly skilled Senior Antibody Discovery Scientist to join our team at Net2Source Inc. as a Scientist Consultant, Antibody Discovery. The ideal candidate will have a strong background in antibody discovery and protein engineering, with significant experience in single B cell cloning, hybridoma, or phage/yeast display...


  • San Francisco, California, United States Strativ Group Full time

    Senior Research ScientistStrativ Group is seeking a pioneering Senior Research Scientist to join our dynamic team at the forefront of biological research. As a key member of our interdisciplinary team, you will work on cutting-edge projects that combine machine learning and generative AI techniques to tackle complex biological challenges.Key...


  • South San Francisco, California, United States eTeam Full time

    Position: Senior Bio-conjugation Research ScientistLocation: South San Francisco, CAContract Duration: 12 monthsCompensation: $66/hrOverview:This role is for a Senior Bio-conjugation Research Scientist within the Discovery Chemistry team at eTeam.• A minimum of 8 years of pertinent industry experience is required, with a Bachelor's or Master's degree, or 5...


  • San Francisco, California, United States Quizlet, Inc. Full time

    Senior Data Scientist, AnalyticsAt Quizlet, Inc., we're seeking a highly skilled Senior Data Scientist to join our analytics team. As a key member of our team, you will be responsible for developing analytical frameworks and foundations to drive business decisions.Key Responsibilities:Develop A/B testing frameworks through the entire experimentation life...


  • San Francisco, California, United States Genentech Full time

    Job OpportunityWe are seeking a highly skilled Senior/Principal Scientist to lead lab-based translational research and discovery efforts in the clinical proteomics and mass spectrometry laboratory at Genentech.Key ResponsibilitiesDesign and execute mass spectrometry/clinical proteomics experiments to explore novel biomarker hypotheses and collaborate with...


  • San Francisco, California, United States city of San Elizario Full time

    About the RoleWe are seeking a highly skilled and experienced Senior Scientist to join our Inflammation Research team in San Elizario. As a key member of our team, you will be responsible for designing and executing experiments to explore and understand the pharmacology of drug targets, generating and communicating pharmacology and preclinical data to...


  • South San Francisco, California, United States Careerbuilder-US Full time

    Job Title: Senior Research Scientist Job Location: South San Francisco, CA Job Duration: 12 months+ Pay Range: $47.50/hr on W2 Shift: (Mon – Fri) 8 AM to 5 PM Position Overview: · The South San Francisco Innovation Center is dedicated to pioneering research initiatives. This cutting-edge, multi-disciplinary research facility is equipped with...


  • San Francisco, California, United States Atomwise Full time

    Senior Scientist in Pharmacology at AtomwiseCompany OverviewAtomwise, a leader in the United States, is revolutionizing the field of drug discovery through the innovative use of Artificial Intelligence (AI). The organization has been at the forefront of integrating deep learning into structure-based drug discovery, resulting in a robust pipeline of potential...


  • San Francisco, California, United States UCSF Benioff Children's Hospitals Full time

    Application Overview: We invite applications for a Senior Research Scientist position within the Baron Lab at UCSF Benioff Children's Hospitals. This role is ideal for individuals with a robust background in experimental laboratory research and proven leadership capabilities necessary for overseeing multiple research initiatives, including collaborations...


  • San Francisco, California, United States UCSF Benioff Children's Hospitals Full time

    Position Overview:The UCSF Benioff Children's Hospitals is actively searching for a Senior Research Scientist at the Full rank.We seek an individual with a robust background in experimental laboratory research and proven leadership capabilities to oversee various research initiatives, including collaborations with academic institutions and industry...


  • San Francisco, California, United States Amazon Full time

    About the RoleWe are seeking a highly experienced and skilled Senior Principal Research Scientist to join our Sustainability team at Amazon. As a key member of our team, you will play a critical role in driving technical strategy and innovation for our long-term sustainability and climate commitments.Key ResponsibilitiesDevelop and implement technical...


  • San Francisco, California, United States Harnham Full time

    Position Overview: We are looking for an experienced and driven Senior Cheminformatics Scientist to join our innovative research team. The ideal candidate will be instrumental in utilizing computational techniques and data analysis to enhance our drug discovery initiatives. As a vital contributor to our organization, the Senior Scientist will work closely...

Senior Scientist

4 months ago


South San Francisco, California, United States Alector Full time

Our mission is to develop therapies that empower the immune system to combat neurodegeneration and our team is focused on developing treatments for some of the most challenging diseases facing our society. We are supported in this mission by experienced and accomplished scientists and clinicians, a novel portfolio of programs, leading healthcare investors, and pharma company partners, who share in our commitment to bettering the lives of patients and realizing a world where we make brain disorders history

As a Senior Scientist specializing in Spatial Transcriptomics for the study of neurodegenerative diseases, you will lead and contribute to our research efforts aimed at unraveling the intricate molecular and cellular mechanisms underlying these conditions. This position offers the unique opportunity to be at the forefront of research that has the potential to drive the development of novel therapeutic strategies for these devastating diseases.

Responsibilities include the development and execution of comprehensive research strategies to investigate the spatial gene expression patterns in neurodegenerative disease models, with a focus on understanding disease progression and potential therapeutic targets. You will oversee and actively engage in the generation of spatial transcriptomics data, from designing and optimizing experimental protocols to conducting experiments. You will collaborate closely with computational biologists, data scientists, and fellow researchers, encouraging interdisciplinary collaboration to extract relevant insights from the data and drive innovative research for Alector's therapeutic pipeline.

During your first year, your goals will include:

  • Successfully initiate at least one spatial transcriptomics research project focused on a specific neurodegenerative disease. This includes project planning, securing necessary resources, and defining clear research objectives.
  • Coordinate the generation of high-quality spatial transcriptomics data for the initiated project. Ensure that the data meet thorough quality standards and reproducibility benchmarks.
  • Make significant progress in the development and implementation of advanced bioinformatics pipelines for spatial transcriptomics data analysis tailored to neurodegenerative diseases.
  • Stay at the forefront of spatial transcriptomics technology and collaborate with interdisciplinary teams to develop and refine experimental protocols tailored to the complexities of neurodegenerative diseases.

We'd love to hear from you if:

  • You have a Ph.D. in a relevant field (e.g., Neuroscience, Molecular Biology, Genomics).
  • You have a minimum of 5 years of post-doctoral research or industry experience with a strong emphasis on spatial transcriptomics, particularly in the context of neurodegenerative diseases.
  • You have a proven expertise in spatial transcriptomics techniques, including sample preparation, sequencing, and data analysis.
  • You are proficient in bioinformatics tools and programming languages commonly used in genomics research (e.g., R, Python).
  • You have a strong track record of publications in peer-reviewed scientific journals, with a focus on neurodegenerative diseases.
  • You have excellent communication and presentation skills.
  • You can work both independently and as part of a collaborative team.
  • You demonstrated leadership and mentorship abilities.

Not required for consideration, but considered as a plus:

You have multi-modal microscopy experience. You have IHC experience from sample preparation to imaging.You have process automation experience.

#LI-RS1

#LI-Onsite

At Alector, our vision is bold, people are our priority, and our values are at the core of everything we do. Our dynamic and flexible environment encourages our teams to experiment, take ownership of decisions, and question convention to solve complex problems. We value shared wins, perseverance, and a growth mindset, which drives us forward, together.

Among the things you'll discover at Alector from your very first day are our committed and driven colleagues, a bold company vision, and new, modern offices designed to inspire innovation and collaboration in South San Francisco, right at the heart of Biotech Bay. Our benefits are thoughtfully designed around Alectorians and their loved ones and include flexible hybrid work options, competitive compensation, and comprehensive and unique benefits that enhance your health and well-being. Come join us

We believe that hard-working teams include people from a wide variety of backgrounds and experiences who can challenge each other's assumptions with fresh perspectives and bring creative ideas to the table. We are committed to building an open, diverse, and inclusive environment for all employees. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, sexual orientation, age, marital status, veteran status, or disability status, or any other characteristics protected under applicable federal, state, or local laws.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, perform essential job functions, and receive other benefits and privileges of employment. Please contact us to request accommodation.

Review our Privacy Policy