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Senior Scientist, Boston Discovery Chemistry

4 months ago


Boston, Massachusetts, United States Merck Full time

Job Description

Our company's Research Laboratories-Boston is focused on driving discovery research. Our fully integrated multi-disciplinary discovery research site offers state-of- the-art resources to explore the most promising science combined with our company's world-class R&D expertise in small molecules and biologics. Located within the heart of Boston's vibrant Longwood biomedical community, research conducted in our laboratories spans exploratory biology through early clinical development and is an integral part of our company's powerful world-class network of drug and vaccine discovery.

At our company, we are inspired by the belief that a research-driven enterprise dedicated to scientific excellence can create medicines and vaccines that save and improve lives. Every employee is building on our proud legacy of scientific breakthrough to impact the lives of patients, which relies on the integrity, creativity, humility, and scientific acumen of our team. We are creating a diverse organization that is inspired by invention and founded on a culture of respect and collaboration. At our Boston site, you will have the opportunity to expand your knowledge and skills through collaboration with talented and dedicated colleagues while advancing your career.

Job Description:

Our Company is currently seeking exceptional chemists to join our Boston site's highly collaborative Discovery Chemistry Department. The successful candidates will contribute to multidisciplinary discovery teams by applying innovative synthetic chemistry, analytical techniques, and data analysis to the design and synthesis of drug candidates and intermediates. Successful candidates must have excellent interpersonal, collaboration, and communication skills in a team environment and a proven record of solving complex problems. It is expected that the successful candidates will learn quickly through on-the-job training to become increasingly skilled in the design, synthesis, and optimization of complex drug candidates and intermediates, and data driven drug design. In addition, there is an opportunity to expand your knowledge and skills through collaborations with talented and dedicated colleagues while advancing your career.

Specific responsibilities will include the following:

  • Act as an expert in the laboratory, executing on program and chemistry strategy.
  • Develop and utilize innovative synthetic, medicinal chemistry and/or chemical biology problem solving skills to build structure-activity relationships.
  • Design, synthesize, purify, and characterize intermediates, drug candidates, and/or chemical probes to enable target identification and validation, hit-to-lead, and lead optimization programs.
  • Provide scientific mentoring and technical training of team members.
  • Establish a substantial external scientific presence including authoring significant scientific publications and presentations.

Education Minimum Requirements:

  • B.S. degree in chemistry, chemical biology, medicinal chemistry, or related scientific discipline with seven (7) years of experience, M.S. degree in related fields with four (4) years of experience or Ph.D. in related fields.

Required Skills and Experience:

  • Prior experience in methodology/catalysis, total synthesis, chemical biology, bioconjugate chemistry, peptide synthesis, and/or physical organic chemistry.
  • Ability to solve complex problems.

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

#EligibleforERP #B

Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.

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U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Regular

Relocation:

Domestic

VISA Sponsorship:

Yes

Travel Requirements:

No Travel Required

Flexible Work Arrangements:

Not Applicable

Shift:

Not Indicated

Valid Driving License:

No

Hazardous Material(s):

Standard Lab Chemicals

Job Posting End Date:

05/22/2024

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Job Posting End Date:05/22/2024

A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID:R291412