Current jobs related to Scientist/Principal Scientist - Cambridge, Massachusetts - Eli Lilly and Company
-
Principal Scientist
3 weeks ago
Cambridge, Massachusetts, United States Novartis Group Companies Full timeJob SummaryWe are seeking an experienced Senior Principal Scientist or Principal Scientist to join our Oncology Research and Development team at Novartis Group Companies. The successful candidate will be responsible for developing and implementing pharmacokinetics and clinical pharmacology strategies to support the development of innovative medicines.Key...
-
Principal Scientist Protein Production
2 days ago
Cambridge, Massachusetts, United States Planet Pharma Full timeJob Title: Principal Scientist, Protein ProductionPlanet Pharma is seeking a highly experienced Principal Scientist to lead our Protein Production team. As a key member of our research and development team, you will be responsible for developing and optimizing upstream and downstream processes to generate lead and Development Candidate molecules.Key...
-
Principal Scientist Nucleic Acid Medicine
3 days ago
Cambridge, Massachusetts, United States Evonik Degussa Corporation Full timeUnlock Your Potential as a Principal Scientist Nucleic Acid MedicineAt Evonik, we're committed to innovation and sustainability. As a Principal Scientist Nucleic Acid Medicine, you'll play a key role in shaping our future. We're seeking a talented and motivated individual to lead and build a Cell Culture team from scratch. This is an exciting opportunity to...
-
Principal Scientist in Drug Development
3 weeks ago
Cambridge, Massachusetts, United States Newton Colmore Full timeAbout the RoleWe are seeking a highly experienced Senior DMPK and ADME Expert to join our research team at Newton Colmore. As a Principal Scientist in Drug Development, you will play a key role in designing and implementing in vivo PK studies, providing updates and results to research teams, and presenting strategies at governance interactions.Key...
-
Principal NLP Machine Learning Scientist
2 weeks ago
Cambridge, Massachusetts, United States DeepRec Full timeJob Title: Principal NLP Machine Learning ScientistAbout the Role:We are seeking a highly skilled Principal Machine Learning Scientist to join our team at DeepRec. As a key member of our team, you will be responsible for developing and training large-scale language models, fine-tuning models with feedback, and integrating multimodal scientific data.Key...
-
Principal Scientist
2 weeks ago
Cambridge, Massachusetts, United States Bristol-Myers Squibb Full timeAbout the RoleBristol-Myers Squibb is seeking a highly skilled Principal Scientist to join our Computational Design and Predictive Modeling team in Cambridge, MA. As a key member of our team, you will play a critical role in developing novel bioinformatics and machine learning solutions to analyze and characterize antibody repertoire sequencing data.Key...
-
Senior Principal Scientist
2 weeks ago
Cambridge, Massachusetts, United States Novartis Group Companies Full timeJob SummaryAs a Senior Principal Scientist in the Translational Medicine Drug Disposition Bioanalytical group at Novartis Group Companies, you will have the opportunity to make a significant impact in the development of novel modality biologics. This vital leadership role requires a collaborative nature, a commitment to teamwork, and a relentless focus on...
-
Principal Scientist Nucleic Acid Medicine
2 weeks ago
Cambridge, Massachusetts, United States WilsonHCG Full timeJob Summary:WilsonHCG is seeking a highly skilled Principal Scientist Nucleic Acid Medicine to join our team in the Cambridge area. As a key member of our Nucleic Acid team, you will be responsible for building a highly functional and collaborative team of Subject Matter Experts in the world of MRNA and LNP.About the Role:This is a great opportunity for...
-
Cambridge, Massachusetts, United States Bristol-Myers Squibb Full timeTransforming Patients' Lives through ScienceBristol-Myers Squibb is a leading biopharmaceutical company dedicated to discovering, developing, and delivering innovative medicines that transform patients' lives. We are seeking a highly skilled and experienced Senior Principal Scientist/Associate Director Neurology to join our Translational Medicine team.About...
-
Principal Scientist, Molecular Biology
2 weeks ago
Cambridge, Massachusetts, United States Generation Bio Full timeJob Summary:Generation Bio is seeking a highly motivated and experienced molecular biologist to join our team as a Principal Scientist. The successful candidate will have a strong background in mammalian cellular trafficking and a deep understanding of nuclear pore complex structure and function.Key Responsibilities:Design and optimize nuclear translocation...
-
Cambridge, Massachusetts, United States The University of Texas MD Anderson Cancer Center Full timeJob Title: Principal/Senior/Scientist, Biomolecular AnalysisJob Summary:We are seeking a highly skilled Senior Scientist, Biomolecular Analysis Specialist to join our team at The University of Texas MD Anderson Cancer Center. As a key member of our research team, you will be responsible for driving the biomolecular characterization to support platform...
-
Principal Research Scientist
4 days ago
Cambridge, Massachusetts, United States Novartis Group Companies Full timeAbout the Role:We are seeking a highly motivated and creative Principal Scientist to join our interdisciplinary team that combines chemical biology, covalent drug discovery, mass spectrometry, cell biology, and informatics technologies to tackle the challenge of identifying covalent small molecules that modulate the activity of undrugged targets and...
-
Cambridge, Massachusetts, United States Flagship Pioneering Full timeAbout the RoleWe are seeking a highly skilled and motivated Translational Multiomics Scientist to join our team at Flagship Pioneering. As a key member of our biomarker discovery and data analysis team, you will play a critical role in developing and applying computational skills to understand complex biological systems and their relationship to clinical...
-
Senior Protein Scientist
1 week ago
Cambridge, Massachusetts, United States Flagship Ventures Full time{"title": "Principal Scientist, Protein Sciences", "company": "Flagship Ventures", "description": "Company OverviewFlagship Ventures is a pioneering technology company that leverages artificial intelligence to transform the scientific method. Our mission-driven team is dedicated to discovering and developing innovative solutions for the life sciences...
-
Cambridge, Massachusetts, United States Flagship Ventures Full timeTransform Human Health and SustainabilityFlagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. We are seeking a talented and highly motivated Principal Scientist, Medicinal Chemistry to join our team.Key ResponsibilitiesDesign and...
-
Senior Principal Scientist in GCP Bioanalysis
3 weeks ago
Cambridge, Massachusetts, United States Novartis Group Companies Full timePosition OverviewJoin our team as a Senior Principal Scientist within the Translational Medicine Drug Disposition Bioanalytical division. This role offers a unique opportunity to enhance your leadership capabilities while contributing to our mission of improving patient outcomes. We seek individuals who thrive in collaborative environments and are dedicated...
-
Principal Scientist
2 weeks ago
Cambridge, Massachusetts, United States Planet Pharma Full timeAbout the RoleWe are seeking an experienced Protein Production and Process Development leader to join our team at Planet Pharma. As a Principal Scientist, you will be responsible for developing and optimizing upstream and downstream processes to generate lead and Development Candidate TCR bispecific molecules.Key ResponsibilitiesDevelop and optimize upstream...
-
Cambridge, Massachusetts, United States Planet Pharma Full timeJob Title: Principal Scientist, Protein ProductionPlanet Pharma is seeking a highly experienced Principal Scientist, Protein Production to join our team in Cambridge, MA. As a key member of our research team, you will be responsible for leading the development and optimization of upstream and downstream processes for protein production.Key...
-
Cambridge, Massachusetts, United States Akebia Therapeutics Full timeJob SummaryWe are seeking a highly skilled Principal Scientist, Drug Product Development to join our CMC Technical Operations team at Akebia Therapeutics. As a key member of our team, you will provide strategic and technical leadership in the development and execution of drug product strategies for our clinical and commercial programs.Key...
-
Lead Scientist, Biomolecular Characterization
4 weeks ago
Cambridge, Massachusetts, United States The University of Texas MD Anderson Cancer Center Full timePosition Title: Lead Scientist, Biomolecular CharacterizationLocation: United StatesPosition Overview:In this role, you will spearhead the biomolecular analysis to facilitate platform innovation and ensure product quality control. Your primary focus will be on the development of bioanalytical assays to evaluate mRNA integrity, capping efficiency,...
Scientist/Principal Scientist
4 months ago
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
We serve an extraordinary purpose. For more than 140 years, we have worked diligently to discover medicines that make life better. These discoveries start in Lilly Research Laboratories, where our scientists work to create new medicines that will help solve our world's greatest health challenges.
At the Lilly Innovation Center in Cambridge, Massachusetts, we explore how next generation therapeutics, new technologies, data analytics and new care models can improve patient health and the healthcare system. Our team in Cambridge shares a real passion for challenging conventional wisdom and creating an environment that embraces creative, break-through concepts. The Center offers a start-up environment with large company support. It is located in the heart of Massachusetts' exploding science and technology cluster and is within walking distance of some of the best academic and industry innovators in the world.
We are seeking an experienced research scientist to join our Genetic Medicine team at Eli Lilly in Indianapolis IN or Cambridge MA. The successful candidate will possess a strong background in synthetic organic chemistry and extensive experience in automated synthesis. She/he will be responsible for synthesizing and characterizing antibody/peptide-RNA conjugates and oligonucleotides to delivery high quality drug molecules, with a focus on effective extrahepatic delivery. The candidate will also design and synthesize functionalized RNAs and develop novel bioconjugation methods in collaborations with a multidisciplinary team.
Job Responsibilities:
Synthesize and characterize antibody-oligonucleotide conjugates to support in-vivo/in-vitro studies.Develop and optimize bioconjugation methodologies to enable antibody conjugation with novel RNA payloads; contribute to development of RNA delivery platforms for extrahepatic tissues.Explore SAR of novel peptides for RNA delivery and synthesize peptide-RNA conjugates as needed.Work productively and safely in the laboratory; and maintain good practice in writing experimental report in an electronic lab notebook.Engage in collaborative efforts with cross-functional teams for biochemical, cellular, and in-vivo imaging evaluation of siRNA conjugates.Communicate experimental results and project progress with supervisor and at team/department meetings.Job QualificationsBachelor's degree in synthetic chemistry, medicinal chemistry, or similar field with 7+ years of drug discovery experience, or Master's degree in a relevant field and 5+ years of drug discovery experience.Additional Skills/PreferencesExtensive knowledge of modern organic and medicinal chemistry; significant contributions to discovery of clinical candidates is advantageous.Experience in peptide and/or oligonucleotide, and multi-molecule conjugation chemistry will be preferred.Understanding advanced analytical and purification techniques.Proficiency in independently executing research tasks.Strong problem-solving skills with creative solutions in constructing complex molecular systems; demonstrate scientific rigors in execution of chemistry plansA proven track record of contributions to research projects, substantiated by issued patents/patent applications or peer-reviewed journal publications.Productive collaborations in interdisciplinary team environment.Excellent communication and organizational skills Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively "Lilly") are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women's Network, Working and Living with Disabilities. Learn more about all of our groups. #WeAreLilly
