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Manager, Clinical Pharmacology
3 months ago
Will join a team of scientists supporting oncology development programs. Will be the Clinical Pharmacology Lead providing clinical pharmacology expertise to a multidisciplinary project team of an oncology program.
ROLE RESPONSIBILITIES
Acts as Clinical Pharmacology representative on Clinical Sub Team and Development Team, as appropriate.Provides the clinical pharmacology components to Clinical Study Protocols, Clinical Study Reports, Clinical Pharmacology plans for programs.Provides clinical pharmacology expertise to oncology project teams including planning, design, and oversight of clinical pharmacology studies with operational assistance from clinical operations colleagues.Participates in implementing model-based drug development using quantitative approaches to address scientific questions arising during drug development.Provides non-compartmental analysis of PK data and executes appropriate PK/PD analyses such as population PK modeling, PK/PD modeling and conducting simulations.Plans relevant PK/PD analyses. Is responsible for integrating knowledge of pharmacokinetics, pharmacodynamics, patient characteristics, and disease states to optimize doses and dosage regimens throughout clinical drug development in collaboration with pharmacometrics and statistics groups (as relevant).Provides recommendations for clinical doses and dosing regimens (including drug-drug interactions, food effect, special group dosing) to the Clinical and Development teams and in regulatory documentation.Responsible for clinical pharmacology contributions to all regulatory documents including Investigator Brochures, EOP2 meetings.Supports the resolution of clinical pharmacology queries from drug regulatory agencies, takes a lead role in writing and reviewing responses to regulatory queries.Work in a matrix environment with a cross-functional clinical team.
BASIC QUALIFICATIONS
PhD in Pharmacokinetics, Clinical Pharmacology, Pharmacometrics, Engineering or PharmDStrong written and verbal communication skills
PREFERRED QUALIFICATIONS
Experience interpreting PK and PK/PD data and integrating this knowledge into the clinical trial and overall clinical program.Hands-on experience with common software tools for PK and PK/PD analyses (e.g., R, NONMEM, Monolix)
Relocation support available
Work Location Assignment:Flexible
The annual base salary for this position ranges from $93,500.00 to $155, In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 12.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | ). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Medical
