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Senior Scientist, Affinity Selections and Biophysics
4 months ago
公開日: Apr 1 2024
GSK is seeking a highly motivated scientist to join the multidisciplinary Encoded Technologies (ET) team. As a member of the ET Affinity Selections and Biophysics Group, you will support small molecule drug discovery programs across GSK with specific accountability for applying biophysics expertise and techniques in hit discovery and validation, and further developing platform capabilities. Additionally, you will represent the group providing biophysics expertise to cross-functional project teams.
The successful candidate will have hands-on experience with biophysics, chemical biology and/or protein biochemistry techniques (e.g., SPR, MST, DSF, affinity purification, alphaLISA, mass-spectrometry). Experience with targeted protein degradation, molecular glues, covalent probes, interrogation of cell lysates, membrane-bound proteins, and/or oligo therapeutics (e.g,. ASOs, AIMers) is a plus. This experience could be from an academic, biotechnology, or pharmaceutical industry setting. We seek a detail-oriented individual with a demonstrated ability to work in a team environment, including good communication and organizational skills, a strong desire to succeed, and the ability to deliver on time.
GlaxoSmithKline is a world leading research-based pharmaceutical company that combines both individual talent & technical resources to create a platform for the delivery of strong growth in a rapidly changing healthcare market. Our mission is to improve the quality of human life by enabling people to do more, feel better, & live longer. GSK is headquartered in London, UK with operations in the US; this opening is located at the Cambridge, MA, USA site.
This role will provide YOU the opportunity to lead key activities to progress YOUR career, these responsibilities include some of the following...
· Deliver decision-making datasets in support of small molecule hit identification and validation programs
· Contribute to advancing the platform technology via evaluation of new equipment and/or development and optimization of new methodologies
· Become a part of the multidisciplinary Encoded Technologies team while working independently
· Interact with other biophysicists, biologists and chemists across multiple GSK R&D sites
· Contribute to data analysis and have a chance to further develop analytical skills
· Contribute to publications, presentations, and collaborations that enhance the visibility of the team
Why You?Basic Qualifications.
· BS with 5 years experience or MS degree in biophysics, biochemistry, bioengineering, biology, or similar discipline.
Preferred Qualifications
· Self-motivated individual with good organizational skills and ability to effectively communicate experimental hypotheses, planning, and conclusions in a clear manner
· Ability to work flexibly within a team and in response to changes in strategic prioritization
· Experience in biophysical binding techniques, e.g., SPR (especially Carterra LSA), MST, nanoDSF, alphaLISA, trFRET, and/or other similar assays.
Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.
Why Us?
GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organization where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to positively impact the health of 2.5 billion people by the end of 2030.
Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We're committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.
If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at US Toll Free) or outside US).
GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.
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