Head of Biology

2 months ago


San Diego, United States Z-Alpha Therapeutics Full time

Z-Alpha Therapeutics is a pharmaceutical company dedicated to the discovery and development of radiotherapeutics targeting key biological pathways for solid tumors. The company has a revolutionary technology platform in the next generation of alpha particle therapy with potential to be a more targeted therapy, increasing efficacy and limiting toxicity compared to competitors in the radiotherapeutics space. The company has a world-class team of scientists with decades of experience and foundational intellectual property that enables the potential to bring multiple drug candidates into the clinic.


JOB SUMMARY:


The Head of Biology will lead the discovery and validation of novel therapeutic targets in oncology, overseeing drug discovery activities from early-stage research to preclinical development. The position also includes mentoring project leaders, managing teams, and fostering cross-functional collaborations to accelerate oncology treatments toward clinical application.


ESSENTIAL DUTIES AND RESPONSIBILITIES:


  • Spearhead the discovery of new, high-value therapeutic targets for the oncology pipeline.
  • Develop and implement strategies for identifying novel targets within specific patient populations.
  • Oversee biology efforts for innovative oncology therapeutic programs, ensuring timely and strategic delivery of actionable data.
  • Prioritize projects and manage resources to support organizational goals.
  • Foster strong cross-functional collaboration within the discovery organization.
  • Effectively communicate scientific progress and strategy internally and externally.
  • Stay informed on competitive intelligence and advancements in oncology by interacting with experts, attending scientific meetings, and reviewing literature.
  • Promote a culture of scientific excellence and support career growth for a team of cancer biologists.
  • Support business development strategies and needs
  • Perform additional duties as assigned.


EDUCATION/KNOWLEDGE/SKILLS/ABILITIES REQUIRED:


  • Ph.D. in Biology-related field, with 12+ years of progressive biotech/pharma experience.
  • Deep understanding of oncology and the current therapeutic landscape.
  • Proven success in moving projects from target discovery to early development, including lead identification and optimization.
  • Strong interpersonal skills, capable of influencing key scientific decisions and collaborating with stakeholders. A strategic thinker able to balance the big picture with detailed program execution.
  • Strong leader who can develop and lead teams to a high level of performance, within an evolving and fast-paced environment.
  • Exceptional communication and presentation skills. Creative thinker who is innovative and open to new ideas and ways of working
  • Experience managing external research collaborations with contract research organizations and academic partners. Experience with regulatory filings (IND, IB, NDA) is preferred. Experience in radiopharmaceuticals is preferred, but not required.


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