Research Scientist II; Cell Line Process Development

2 months ago

Hopkinton, United States Curia Full time
Job Description

RESEARCH SCIENTIST II, CELL LINE PROCESS DEVELOPMENT in Hopkinton, MA

Curia provides global contract research and manufacturing services to the pharmaceutical and biotechnology industries.

We are rapidly growing and seeking a talented individual for the role of Research Scientist II to join our Process Development team based on Hopkinton, MA. The successful candidate will be able to lead and execute laboratory procedures and perform stable cell line development and expression of recombinant proteins and antibodies to support manufacturing. Strong candidate will have extensive experience in mammalian cell culture engineering to develop highly productive upstream processes.

Join our talented workforce, where a commitment to excellence and a customer focused attitude is everything. We pursue excellence because our work has the power to improve patients’ lives with the pharmaceuticals we develop and manufacture.

We proudly offer

  • Generous benefit options (eligible first day of employment)
  • Paid training, vacation and holidays (vacation accrual begins on first day of employment)
  • Career advancement opportunities
  • Education reimbursement
  • 401k program
  • Pension (for union employees)
  • Learning platform

And more

Responsibilities

  • Serve as a subject matter expert in cell line development to represent functional area for biologics pipeline programs.
  • Perform processes including transfection, cloning, characterization, and production optimization to RCB using modern Advanced Instruments and Sartorius equipment.
  • Conduct operations of clone screening and identifying of target leaders to develop and optimize stable CHO and HEK293 cell lines suitable for manufacturing.
  • Participate in designing and implementing new methods to expand throughput and capacity for CHO cell line process.
  • Represent cell line development on multiple projects and effectively communicate results, progress and plans to colleagues and clients
  • Interface and collaborate with other functional teams in Discovery, Analytics, QA/QC
  • Responsible for technical reports and study records

Qualifications

  • MS (2+ years industry experience) or BS. (+4 years industry experience) in Biochemistry, Molecular Biology, [KD1] Biophysics, Biology, Chemistry, or Chemical Engineering.
  • Track record of accomplishments in the design, development, and implementation of cell culture processes for protein production.
  • Extensive hands-on experience with molecular cloning and vector construction is required. [KD2]
  • Experience with VIPS® Seeder, Ambr® 15 bioreactor or equivalents preferred.
  • Experience optimizing cell lines a plus.
  • Knowledge of bioreactor process and engineering scaling as well as robust understanding of biochemistry and cell metabolic pathways.
  • Must be able to clearly and accurately present written data and be comfortable with oral presentations.

Knowledge, Skills And Abilities

  • The successful candidate will be responsible for implementing cell line development to support our proprietary cell line technology.
  • Candidate must have an in-depth understanding of cell biology and hands-on experience of molecular techniques and mammalian culture.
  • This role will encompass aspects of upstream process development to support to multiple projects as needed. Candidate will support upstream process design, optimization, and tech transfer.
  • The candidate will be responsible for executing projects within the laboratory, writing study/research plans, and summarizing data to clients and colleagues via technical reports.
  • Candidate must be able to work independently, including planning, trouble shooting and execution of daily activities.

Education, experience, location and tenure may be considered along with internal equity when job offers are extended.

We do not accept unsolicited assistance from any headhunters or recruitment firms for any of our job openings. All resumes or profiles submitted by search firms to any employee at Curia, in any form without a valid, signed search agreement by an authorized signatory in place for the specific position, approved by Talent Acquisition, will be deemed the sole property of Curia. No fee will be paid in the event the candidate is hired by Curia because of the unsolicited referral.

All interested applicants must apply online. Please be aware of scammers. Curia will only send offer letters and requests for sensitive personal information from a curiaglobal.com email address. Curia is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Curia is an E-Verify employer.

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