Contract Scientist, In Vivo Cancer Biology
6 months ago
Contract Scientist, In Vivo Cancer Biology
- Part-time position
- Competitive compensation
- 430 E 29th Street, New York
Waypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors, including CAR-T, CAR-NK, and TCR-T. Traditional cell therapy development faces a trade-off between in vitro approaches that are fast but inaccurate, and in vivo approaches that are accurate but slow and expensive. Using our proprietary platform combining spatial biology, pooled screening, in silico protein engineering, and machine learning, we can obtain both depth and breadth when screening cell therapy candidates – speed without compromising on in vivo accuracy. Our team is highly collaborative, interdisciplinary, and shares the mission of bringing the promise of immune cell therapy to all cancer patients.
Position Summary:
We are seeking a highly-motivated part-time scientist who thrives in a fast-paced and collaborative environment. The ideal candidate will have expertise working with mouse cancer models (xenograft solid tumors) to test the efficacy and safety of cancer therapies. Top candidates will also have knowledge and experience performing in vivo tests of CAR-T efficacy in solid tumor models. In this position, you will optimize the performance of our existing solid tumor models and also develop novel mouse models of solid tumors. You will use these models to compare the efficacy of top-performing cell therapy designs, and also to evaluate hundreds of CAR-T designs in vivo using Waypoint’s pooled CAR-T screening platform.
Duties and Responsibilities
- Perform all steps of in vivo mouse studies to assess CAR T efficacy in CDX models. This includes subcutaneous injections for tumor implantation, measuring tumor growth over time, performing IV tail vein and intraperitoneal injections to deliver therapeutic agents, assessing humane & experimental endpoints in the mice, and harvesting tumors for subsequent ex vivo analysis.
- Use mouse cancer models to apply Waypoint’s pooled CAR-T screening platform in vivo.
- Establish new in vivo cancer models and improve the performance and accuracy of existing models.
- Actively engage in prioritizing key milestones and developing appropriate timelines.
- Provide conceptual input on in vivo experimental design and interpretation in a team setting.
- Keep detailed scientific records in electronic lab notebook.
Required Qualifications
- Bachelor’s degree in biology, immunology, genetics, cancer biology, or related field.
- 3+ years of academic or industry experience working on mouse models of solid tumors.
- Technical expertise in mouse injection methods (IV, SubQ, IP), subcutaneous tumor implantation and measurements, organ harvesting, animal phenotyping, and adherence to IACUC protocols.
- Experience with mammalian cell culture.
- Detailed scientific record keeping in electronic format.
- An excellent scientific track record with published papers or recent experience in the fields of cancer biology or immunotherapy.
- Superb organizational abilities and precise scientific record keeping in electronic lab notebooks.
Preferred Qualifications
- Experience using luciferase reporters for live-animal imaging.
- Knowledge of the interplay between the immune system and the tumor microenvironment.
- Expertise in evaluating cancer therapies in mouse models, especially cell therapies (CAR-T, CAR-NK, TCR-T) or antibody therapies.
Send CV and cover letter to apply:
jobs@waypointbio.com
-
Contract Scientist, In Vivo Cancer Biology
1 month ago
new york city, United States Waypoint Bio Full timeContract Scientist, In Vivo Cancer BiologyPart-time positionCompetitive compensation430 E 29th Street, New YorkWaypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors, including CAR-T, CAR-NK, and TCR-T. Traditional cell therapy development faces a trade-off between in vitro approaches that are fast...
-
Contract Scientist, In Vivo Cancer Biology
2 months ago
new york city, United States Waypoint Bio Full timeContract Scientist, In Vivo Cancer BiologyPart-time positionCompetitive compensation430 E 29th Street, New YorkWaypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors, including CAR-T, CAR-NK, and TCR-T. Traditional cell therapy development faces a trade-off between in vitro approaches that are fast...
-
Scientist / Senior Scientist, In Vivo Cancer Biology
2 months ago
New York, United States Waypoint Bio Full timeScientist / Senior Scientist, In Vivo Cancer BiologyFull-time positionCompetitive compensation (Salary, Benefits & Options)180 Varick Street, New York, and 430 E 29th Street, New YorkWaypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors and autoimmune diseases. Traditional cell therapy development...
-
Scientist / Senior Scientist, In Vivo Cancer Biology
2 months ago
new york city, United States Waypoint Bio Full timeScientist / Senior Scientist, In Vivo Cancer BiologyFull-time positionCompetitive compensation (Salary, Benefits & Options)180 Varick Street, New York, and 430 E 29th Street, New YorkWaypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors and autoimmune diseases. Traditional cell therapy development...
-
Scientist / Senior Scientist, In Vivo Cancer Biology
2 months ago
new york city, United States Waypoint Bio Full timeScientist / Senior Scientist, In Vivo Cancer BiologyFull-time positionCompetitive compensation (Salary, Benefits & Options)180 Varick Street, New York, and 430 E 29th Street, New YorkWaypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors and autoimmune diseases. Traditional cell therapy development...
-
Associate Scientist
3 months ago
New York, United States Waypoint Bio Full timeAssociate Scientist / Senior Associate ScientistFull-time positionCompetitive compensation (Salary, Benefits & Options)180 Varick Street, New York, NY, and 430 E 29th Street, New YorkWaypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors and autoimmune diseases. Traditional cell therapy development...
-
Associate Scientist
3 months ago
new york city, United States Waypoint Bio Full timeAssociate Scientist / Senior Associate ScientistFull-time positionCompetitive compensation (Salary, Benefits & Options)180 Varick Street, New York, NY, and 430 E 29th Street, New YorkWaypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors and autoimmune diseases. Traditional cell therapy development...
-
Associate Scientist
3 months ago
new york city, United States Waypoint Bio Full timeAssociate Scientist / Senior Associate ScientistFull-time positionCompetitive compensation (Salary, Benefits & Options)180 Varick Street, New York, NY, and 430 E 29th Street, New YorkWaypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors and autoimmune diseases. Traditional cell therapy development...
-
Postdoctoral Training Fellow
2 weeks ago
New York, United States The Institute of Cancer Research Full timeUnder the leadership of Dr Rachael Natrajan, we are seeking to appoint aPostdoctoral Training Fellow to join our Functional Genomics team. Triple negative breast cancer (TNBC) is an aggressive form of breast cancer characterised by high levels of molecular heterogeneity that underpin its high recurrence rate after neoadjuvant immunotherapy and chemotherapy....
-
New York, United States Waypoint Bio Full timeScientist / Senior Scientist, Immunology (Treg and CAR T cell therapy)Full-time positionCompetitive compensation (Salary, Benefits & Options)180 Varick Street, New York, and 430 E 29th Street, New YorkWaypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors and autoimmune diseases. Traditional cell...
-
new york city, United States Waypoint Bio Full timeScientist / Senior Scientist, Immunology (Treg and CAR T cell therapy)Full-time positionCompetitive compensation (Salary, Benefits & Options)180 Varick Street, New York, and 430 E 29th Street, New YorkWaypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors and autoimmune diseases. Traditional cell...
-
new york city, United States Waypoint Bio Full timeScientist / Senior Scientist, Immunology (Treg and CAR T cell therapy)Full-time positionCompetitive compensation (Salary, Benefits & Options)180 Varick Street, New York, and 430 E 29th Street, New YorkWaypoint Bio is a venture-backed biotech startup building the next generation of cell therapies for solid tumors and autoimmune diseases. Traditional cell...
-
New York, New York, United States Memorial Sloan Kettering Full timeJob Summary:The Kung Lab at Memorial Sloan Kettering Cancer Center is seeking a highly motivated and successful individual to join our team as a Research Scientist in Cancer Genetics and Epigenetics.Key Responsibilities:Develop and evaluate cell therapy-based approaches for the treatment of pediatric cancer.Lead the development and evaluation of novel...
-
Data Scientist, Cancer Research Innovator
4 weeks ago
New York, New York, United States Memorial Sloan Full timeThe Memorial Sloan Kettering Cancer Center (MSK) is at the forefront of cancer research, with a mission to end cancer for life. As a Data Scientist in our Cancer Research Innovator role, you will be part of a dynamic team that develops novel data science and machine learning methods to address pressing needs in cancer research.We are seeking a highly...
-
Research Scientist
4 weeks ago
New York, New York, United States Evolutionary Scale Full timeEvolutionaryScale is a pioneering company in the field of artificial intelligence and biology. We are committed to developing cutting-edge AI solutions that benefit human health and society. Our mission is to advance the field of biology through open, safe, and responsible research, in partnership with the scientific community.Key Responsibilities:Work at...
-
Postdoctoral Research Scientist
3 months ago
New York, United States Columbia University Full timeThe Division of Surgical Science of Surgery at Columbia University Vagelos College of Physicians and Surgeons is accepting applications for a Postdoctoral Research Scientist. Under the supervision of the Principal Investigator, the individual will train in developing and participating in a research project that focuses on cellular and molecular mechanism...
-
Postdoctoral Research Scientist Position
3 weeks ago
New York, New York, United States Columbia University Full timeThe Division of Surgical Science of Surgery at Columbia University Vagelos College of Physicians and Surgeons is seeking a highly skilled Postdoctoral Research Scientist to join our team. Under the supervision of the Principal Investigator, the individual will train in developing and participating in a research project that focuses on cellular and molecular...
-
New York, New York, United States Columbia University Full timeThe Division of Surgical Science at Columbia University Vagelos College of Physicians and Surgeons is seeking a highly motivated Postdoctoral Research Scientist to join our team. The successful candidate will work under the supervision of the Principal Investigator to develop and participate in a research project focused on cellular and molecular mechanisms...
-
Research Scientist
3 weeks ago
New York, New York, United States Waypoint Bio Full timeJob SummaryWe are seeking a highly organized and enthusiastic research professional to join our team at Waypoint Bio. As a Research Scientist, you will have the opportunity to develop scientific knowledge and skills while providing technical support. You will work collaboratively on multiple projects, including cell culture, lentivirus production, and...
-
New York, New York, United States Memorial Sloan Kettering Cancer Center Full timeAbout the OpportunityThe Gastrointestinal Oncology Service in the Department of Medicine at Memorial Sloan Kettering Cancer Center is seeking a full-time early career investigator in gastroesophageal cancer translational research. This physician-scientist will focus on patient care, research, and education for esophageal and gastric cancers, with a one-year...
