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Director, Translational Sciences

4 months ago

Boston MA, United States X4lifesciences Full time

Job Title: Director, Translational Sciences

Company Overview: Join a dynamic and innovative clinical stage biotechnology company dedicated to developing novel antibody-based therapeutics for oncology targets.

Position Overview: We are seeking a highly motivated and experienced Director, Translational Sciences to lead translational research efforts supporting their oncology drug development programs. The successful candidate will play a pivotal role in advancing the pipeline from preclinical stages through clinical development, leveraging their expertise in translational medicine, biomarker development, and oncology/immunology.

Key Responsibilities:

  1. Translational Strategy Development: Develop and execute translational medicine strategies aligned with overall drug development goals, integrating preclinical and clinical data to inform decision-making.
  2. Biomarker Discovery and Development: Lead biomarker discovery efforts to identify and validate predictive and pharmacodynamic biomarkers, facilitating patient stratification and treatment response monitoring.
  3. Clinical Trial Support: Provide translational medicine expertise to clinical development teams, contributing to study design, protocol development, and biomarker-driven patient selection strategies.
  4. Collaboration: Collaborate closely with cross-functional teams including Research, Clinical Development, Biomarker Discovery, and External Partners to drive translational research initiatives and ensure seamless transition from preclinical to clinical stages.
  5. Data Analysis and Interpretation: Analyze and interpret complex translational data sets, generating actionable insights to guide therapeutic development decisions.
  6. External Engagement: Represent the company externally, fostering collaborations with academic institutions, contract research organizations (CROs), and key opinion leaders to advance translational research goals.

Qualifications:

  • Ph.D. or M.D. with significant industry experience in translational medicine, oncology, or related field.
  • Demonstrated track record of success in leading translational research efforts within the biopharmaceutical industry, with specific experience in antibody-based drug development for oncology/immunology.
  • Expertise in biomarker discovery and development, including proficiency in molecular and cellular techniques, genomics, and bioinformatics.
  • Strong understanding of clinical trial design and execution, with experience in biomarker-driven clinical development strategies.
  • Excellent analytical and problem-solving skills, with the ability to critically evaluate complex scientific data and draw meaningful conclusions.
  • Proven ability to thrive in a fast-paced, collaborative environment, with strong communication and leadership skills.
  • Prior experience in a leadership or supervisory role is preferred.

Location: This position is based in Boston, MA and will require 5 days a week on-site.

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